Key pituitary miRNAs mediate the expression of pig GHRHR splice variants by regulating splice factors

Teng, Zhaohui; Hao, Linlin; Yang, Rui; Song, Jié; Wang, Zhaoguo; Jiao, Yingying; Fang, Jiayuan; Zheng, Shuo; Ma, Ze; Chen, Xi; Liu, Songcai; Cheng, Yi

doi:10.1016/j.ijbiomac.2022.03.070

International Journal of Biological Macromolecules

2022

DOI: 10.1016/j.ijbiomac.2022.03.070

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Key pituitary miRNAs mediate the expression of pig GHRHR splice variants by regulating splice factors

Zhaohui Teng

Linlin Hao

Rui Yang

et al.

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2024

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A New Perspective on Pig Genetics and Breeding: microRNA

Xiang,

Yang,

et al. 2024

Reprod Domestic Animals

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ABSTRACTmicroRNA (miRNA) is a class of small non‐coding RNA molecules that are widely expressed in organisms and play an important role in the regulation of gene expression at the post‐transcriptional level. In recent years, researchers have begun to explore its effects on the development of domestic animals and have begun to think about its potential role in modern molecular breeding. Increasing evidence shows that miRNA play a central role in the regulation of pig fertility, pork product quality and disease resistance. Understanding the physiological mechanism of miRNA will be able to better guide future breeding work. In this paper, we will review the research progress of the function and mechanism of miRNA in combination with the above economic characteristics of pigs. The reported miRNA and their target genes were sorted out to evaluate their potential role in improving economic traits such as pig fertility, meat quality and disease resistance, to provide a reference for modern pig molecular breeding.

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A New Perspective on Pig Genetics and Breeding: microRNA

Xiang,

Yang,

et al. 2024

Reprod Domestic Animals

View full text Add to dashboard Cite

show abstract

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Key pituitary miRNAs mediate the expression of pig GHRHR splice variants by regulating splice factors

Cited by 1 publication

References 47 publications

A New Perspective on Pig Genetics and Breeding: microRNA

A New Perspective on Pig Genetics and Breeding: microRNA

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