KI-mediated three-component annelation for the regioselective synthesis of angular azolo[1,5-a]pyrimidine derivatives

Abstract

A straightforward and regioselective avenue to angular azolo[1,5-a]pyrimidine derivatives via the three-component cyclization of aldehydes and α-aminoazoles with cycloketones is presented. The initiation of the condensation reaction between aldehydes and...