Kidney Stone Dissolution Therapy in Phosphate Stones: A Case Report

Schillebeeckx, Charlotte; Eeckt, Kathy Vander; Ost, David; Branden, Marcel Van Den; Deconinck, Steven

doi:10.1089/cren.2019.0076

Cited by 4 publications

(2 citation statements)

References 4 publications

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“…The medical management of uric lithiasis (calculation of pure uric acid and mixed calculation of uric acid and calcium oxalate) therefore requires the maintenance of a diuresis greater than two liters per 24 hours, but also an increase of urine pH, with the objective of a urine pH between 6.2 and 6.8 for preventive medical treatment, and 7 to 7.2 for dissolution of uric acid stones (pure) in place [22]. In our study, uric acid is very remarkable and ahead of calcium oxalate with a rate of 46.80%, which requires in-depth studies to find the causes of the predominance of uric acid in the urine of lithiasics in the Tissemsilt region.…”

Section: Uric Acidsmentioning

confidence: 99%

Search for Crystalline Species of Urinary Stones by Patients in the Region of Tissemsilt, Algeria

Beghalia¹,

Mendi²,

Derri³

2021

Ukr. ž. med. bìol. sportu

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Urinary stones are among the most common diseases in the world and in Algeria as well, because it is a complex and multifactorial disease. The saturation of solutes in the urine is considered as the main stage of the deposition of crystals and their rapid growth and aggregation lead to the formation of stones in different places of the urinary system. It is the consequence of excessive urinary supersaturation causing renal complications such as lithiasis, nephrocalcinosis, acute or chronic renal failure which may progress to the terminal stage. The purpose of the study was to identify the most common different forms of crystals in the urine of patients for further measures to prevent more serious complications of crystalluria. Materials and methods. The study focused on all lithiasis patients of the age group "from 20 years to 84 years". Three-day urine samples were collected at different urology departments which were referred by urologists, during the period from February 06, 2020 to March 21, 2020. Being the best method, crystalluria was used to determine the types of crystals, their number and their growth. Three criteria must be met for the study of crystalluria to be clinically interpretable. They are the choice of patients according to their metabolic state; how long urine is stored after it is released, and the storage temperature. Results and discussion. Thanks to this study it was possible to characterize many types of crystals, including calcium oxalates, in particular monohydrate, which is considered as a risk factor for stone formation. Also, the urinary acid crystals indicate a specific environmental pattern in many patients. In addition to the calcium phosphate crystals resulting from microbial infections, the results showed pure crystalline aggregates which will inevitably lead to lithiasis. The microscopic examination of patient urine samples is the preferred method for optimal patient assurance with the cooperation of therapists and doctors in addition to the epidemiological study. Conclusion. The relatively high rate of recurrent lithiasis illustrates the current limits of preventive measures which can be penalized by the lack of patient attendance but whose reduced effectiveness primarily suggests a lack of knowledge of one or more fundamental determinants of the lithogenic process. The experimental part showed a diversity of crystals in the urine of patients, pure calcium oxalate monohydrate, which was noticed in the majority of the subjects analyzed. The detection, in crystalluria, of a single crystal of whewellite can therefore be considered as a marker for hyperoxaluria. Weddellite was more common in the urine of subjects under analysis

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Section: Uric Acidsmentioning

confidence: 99%

Search for Crystalline Species of Urinary Stones by Patients in the Region of Tissemsilt, Algeria

Beghalia¹,

Mendi²,

Derri³

2021

Ukr. ž. med. bìol. sportu

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“…But in recent years, treatment has become less common because of potential risk concerns and the development of less invasive stone surgery. Despite the Food and Drug Administration reapproval of Renacidin's use, less information about chemolysis is now accessible (7). The purpose of this research is to review the available information about overview of oral chemolysis types and its effectiveness in treating kidney stones.…”

Section: Introductionmentioning

confidence: 99%

Overview of Oral Chemolysis Types and Its Effectiveness in Treating Kidney Stones

Alqahtani¹,

Faydh²,

Thobaiti³

et al. 2022

JOHS

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One of the most often diagnosed urological disorders is kidney stones with a prevalence which varies between 5% and 10% globally. In 1924, Crowell presented the first description of stone disintegration by direct irrigation. Since then, chemolysis-based dissolution therapy has been applied for the treatment of kidney stones in both primary and adjuvant settings, with different degrees of success. Depending on the type of stone, several chemolysis techniques can be applied. It has been suggested that d-penicillamine, tromethamine-E or tiopronin, and Nacetylcysteine can dissolve cystine stones. While phosphate stones are known to dissolve in acidic solutions. Renacidin and Suby G are two of the most common compounds used for chemolysis. Chemolysis can be utilized as a stand-alone therapy or as an adjuvant to shock wave lithotripsy, percutaneous nephrolithotomy, or open stone removal. The purpose of this research is to review the available information about overview of oral chemolysis types and its effectiveness in treating kidney stones. Oral chemolysis is a safe and effective treatment modality for patients with kidney stones. However, oral chemolysis is infrequently used despite the potential benefit of avoiding stone surgery with all its potential risks. The absence of trustworthy predictors of its outcome and the scarcity of high-quality data on its effectiveness are two factors contributing to its restricted utilization further clinical trialbased research is therefore needed to elaborately study the efficacy profile of oral chemolysis on various stone sizes and types.

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Dissolution of struvite stones with ascorbic acid

Yoshikawa

2025

Urology Case Reports

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Kidney Stone Dissolution Therapy in Phosphate Stones: A Case Report

Cited by 4 publications

References 4 publications

Search for Crystalline Species of Urinary Stones by Patients in the Region of Tissemsilt, Algeria

Search for Crystalline Species of Urinary Stones by Patients in the Region of Tissemsilt, Algeria

Overview of Oral Chemolysis Types and Its Effectiveness in Treating Kidney Stones

Dissolution of struvite stones with ascorbic acid

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