Kimura's disease and its relation to angiolymphoid hyperplasia with eosinophilia: report of three cases and review of the literature

Abstract

Kimura's disease, eosinophilic granuloma of soft tissues, is a chronic inflammatory condition and appears as subcutaneous tumor‐like nodules in the head and neck regions. Histopathologically, it is characterized by the presence of lymphoid follicles, marked infiltration of eosinophils, fibrosis and vascular proliferation. This disease occurring in the orofacial region is relatively rare, only 14 cases having been previously reported. We describe 3 additional cases of Kimura's disease and discuss these in relation to angiolymphoid hyperplasia with eosinophilia.

Kimura's Disease with Asthma in Turkish Woman

“…9 Hastalık subkütan dokuda lenfosit ve eozinofillerden baskın infiltre lenfoid foliküller, fibroz ve vasküler proliferasyonla seyretmektedir. 10 Olgumuzda görülen periferik kan tablosu ve patolojik özellikler Kimura hastalığının genel özellik-leri ile kolerasyon göstermektedir.…”

Kimura’s Disease of the Intraparotid Lymph Nodes: Fine Needle Aspiration Biopsy Findings

“…Other sites of involvement are the oral cavity, axilla, groin, popliteal region and forearm. Increased IgE serum levels and peripheral blood eosinophilia are generally detected [7,[16][17][18]. Renal disease may also be associated [19,20].…”

Angiolymphoid Hyperplasia With Eosinophilia: A Classic Clinical Presentation With Histologic Features of Angiosarcoma

“…3,4 The histopathology of ALHE can be quite varied from case to case, leading to a broad and interesting differential diagnosis in some instances. Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare disease manifested by the proliferation of morphologically distinct endothelial cells.…”