2005
DOI: 10.1002/chin.200534040
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Kinetic Resolution and Chemoenzymatic Dynamic Kinetic Resolution of Functionalized γ‐Hydroxy Amides.

Abstract: Biochemical syntheses O 0035Kinetic Resolution and Chemoenzymatic Dynamic Kinetic Resolution of Functionalized γ-Hydroxy Amides. -In the presence of Pseudomonas cepacia lipase efficient kinetic resolution and dynamic kinetic resolution of hydroxyl amides are possible. The enantiomerically enriched hydroxyl amides can easily be converted into other interesting compounds such as the lactone (IV). -(FRANSSON, A.-B. L.; BOREN, L.; PAMIES, O.; BAECKVALL*, J.-E.; J. Org. Chem. 70 (2005) 7, 2582-2587; Dep. Org. Chem.… Show more

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