Kinetic study of chitosan-tripolyphosphate complex reaction and acid-resistive properties of the chitosan-tripolyphosphate gel beads prepared by in-liquid curing method

Mi, Fwu Long; Shyu, Shin Shing; Lee, Sung-Tao; Wong, Tsung-Bi

doi:10.1002/(sici)1099-0488(19990715)37:14<1551::aid-polb1>3.0.co;2-h

Cited by 211 publications

(143 citation statements)

References 24 publications

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“…CS microparticles were dissolved in different solvents like water, ethanol, phosphate buffer saline (PBS pH 6) and acetic acid at the concentration of 1 mg ml -1 and used to study the drug release kinetics. Absorbanace at 425nm asymmetric stretching vibration of the PO 2 groups), 1090-1115 (symmetric and asymmetric stretching vibration of the PO 3 groups) and 880-895 cm -1 (P-O-P asymmetric stretching) (Mi et al 1999;Martins et al 2012) (Fig. 1a, c, e).…”

Section: Antibacterial Activitymentioning

confidence: 99%

Chelators influenced synthesis of chitosan–carboxymethyl cellulose microparticles for controlled drug delivery

et al. 2016

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In this study, polyphenolic curcumin is entrapped within microcomposites made of biopolymers chitosan (CS) and carboxymethyl cellulose (CMC) formulated by ionic gelation method. Here, different concentrations of two chelating agents, barium chloride and sodium tripolyphosphate, are used to make microcomposites. Thus, the synthesized microparticles were characterized by FTIR, and their surface morphology was studied by SEM. Drug encapsulation efficiency and the drug release kinetics of CS-CMC composites are also studied. The produced microcomposites were used to study antibacterial activity in vitro.

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Section: Antibacterial Activitymentioning

confidence: 99%

Chelators influenced synthesis of chitosan–carboxymethyl cellulose microparticles for controlled drug delivery

et al. 2016

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“…TPP는 무독성의 polyanion으로, 정전기적 힘으로 키토산과 상호작용하여 이온결 합을 생성한다. TPP는 빠른 겔화 능력 때문에 구형의 키토산 비드 형성에 사용될 수 있다 [15]. 또한 ECH는 염기 촉매 가 교제로 사용되었다.…”

Section: Methodsunclassified

Properties of Cellulase Immobilized on Chitosan Beads

Lee¹,

Ha²,

Kim³

et al. 2014

KSBB Journal

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Abstract:Recently, there is a growing interest in efficient biomass pretreatment and saccharification processes to produce biofuels and biochemicals from renewable non-food biomass resources. In this study, glucose was produced from cellulose by immobilizing cellulase enzyme on chitosan beads which was reported to have high pH and temperature stability. The immobilized amounts of cellulase on chitosan beads linearly increased with increasing the concentrations of cellulase solution. The glucose production increased to 7.2 g/L from 1% carboxymethyl cellulose (CMC) substrate when immobilized at 20% cellulase solution. The maximum specific activity was 0.37 unit/mg protein when immobilized at 8% cellulase solution. At pH 7 and 37 o C, the optimum reaction composition was 0.5 g beads/L from 1% CMC substrate. At this condition, the conversion to glucose completed at ca. 20 min.

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“…46,47 All other remaining spectra showed a broad O−H stretch peak at ∼3425 cm −1 and peak at ∼2900 cm −1 for the C−H stretch. CM-β-CD sodium salt (Figure 2b) had bands at 1419 and 1602 cm −1 corresponding to the symmetrical and asymmetrical stretching vibration of the carboxylate groups, respectively.…”

Section: Ft-irmentioning

confidence: 99%

pH-Triggered Release of Hydrophobic Molecules from Self-Assembling Hybrid Nanoscaffolds

Lü

Unsworth

2016

Biomacromolecules

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Vous avez des questions? Nous pouvons vous aider. Pour communiquer directement avec un auteur, consultez la première page de la revue dans laquelle son article a été publié afin de trouver ses coordonnées. Si vous n'arrivez pas à les repérer, communiquez avec nous à PublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. Questions? Contact the NRC Publications Archive team atPublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. If you wish to email the authors directly, please see the first page of the publication for their contact information. NRC Publications Archive Archives des publications du CNRCThis publication could be one of several versions: author's original, accepted manuscript or the publisher's version. / La version de cette publication peut être l'une des suivantes : la version prépublication de l'auteur, la version acceptée du manuscrit ou la version de l'éditeur. For the publisher's version, please access the DOI link below./ Pour consulter la version de l'éditeur, utilisez le lien DOI ci-dessous.http://doi.org/10.1021/acs.biomac.6b00040Access and use of this website and the material on it are subject to the Terms and Conditions set forth at pH-triggered release of hydrophobic molecules from self-assembling hybrid nanoscaffolds Lu, Lei; Unsworth, Larry D.http://nparc.cisti-icist.nrc-cnrc.gc.ca/fra/droits L'accès à ce site Web et l'utilisation de son contenu sont assujettis aux conditions présentées dans le site LISEZ CES CONDITIONS ATTENTIVEMENT AVANT D'UTILISER CE SITE WEB. NRC Publications Record / Notice d'Archives des publications de CNRC:http://nparc.cisti-icist.nrc-cnrc.gc.ca/eng/view/object/?id=9e4287db-e138-42bd-a2f4-805f4418351b http://nparc.cisti-icist.nrc-cnrc.gc.ca/fra/voir/objet/?id=9e4287db-e138-42bd-a2f4-805f4418351b pH-Triggered Release of Hydrophobic Molecules from SelfAssembling Hybrid Nanoscaffolds Lei Lu †, ‡ and Larry D. Unsworth* , †, ‡ † Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Alberta T6G 2V4, Canada ‡ National Institute for Nanotechnology, National Research Council (Canada), Edmonton, Alberta T6G 2M9, Canada * S Supporting Information ABSTRACT: Self-assembling peptide based hydrogels have a wide range of applications in the field of tissue repair and tissue regeneration. Because of its physicochemical properties, (RADA) 4 has been studied as a potential platform for 3D cell culture, drug delivery, and tissue engineering. Despite some small molecule and protein release studies with this system, there is a lack of work investigating the controlled release of hydrophobic compounds (i.e., anti-inflammatory, anticancer, antibacterial drugs, etc.) that are important for many clinical therapies. Attempts to incorporate hydrophobic compounds into self-assembling matrices usually inhibited nanofiber formation, rather resulting in a peptide−drug complex or microcrystal formation. Herein, a selfassembling chitosan/carboxymethyl-β-cyclodextrin nanoparticle system was used to load dexamethasone, which formed within a self-assembling (RADA...

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Kinetic study of chitosan-tripolyphosphate complex reaction and acid-resistive properties of the chitosan-tripolyphosphate gel beads prepared by in-liquid curing method

Cited by 211 publications

References 24 publications

Chelators influenced synthesis of chitosan–carboxymethyl cellulose microparticles for controlled drug delivery

Chelators influenced synthesis of chitosan–carboxymethyl cellulose microparticles for controlled drug delivery

Properties of Cellulase Immobilized on Chitosan Beads

pH-Triggered Release of Hydrophobic Molecules from Self-Assembling Hybrid Nanoscaffolds

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