Kinetics, composition and antioxidant activity of burdock (Arctium lappa) root extracts obtained with supercritical CO2 and co-solvent

Rodriguez, João Manoel Folador; Souza, Ariádine Reder Custódio de; Krüger, Roberta Letícia; Bombardelli, Michele Cristiane Mesomo; Machado, Christiane Schineider; Corazza, Marcos L.

doi:10.1016/j.supflu.2017.12.034

Cited by 38 publications

(15 citation statements)

References 57 publications

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“…Burdock ( Arctium lappa ) is a popular traditional medical plant from Asia, America, and Europe belonging to the Asteraceae family. Based on the phenolic-rich compounds present in the extract, burdock has antimicrobial and antioxidant capabilities, as well as other biochemical activities including antipyresis and detoxifying [ 231 , 232 , 233 , 234 , 235 ]. Therefore, this plant could be used as an antioxidant, antimicrobial, and anti-inflammatory agent [ 60 , 236 ].…”

Section: Antimicrobial Agentmentioning

confidence: 99%

Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials

et al. 2020

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Recently, increasing public concern about hygiene has been driving many studies to investigate antimicrobial and antiviral agents. However, the use of any antimicrobial agents must be limited due to their possible toxic or harmful effects. In recent years, due to previous antibiotics’ lesser side effects, the use of herbal materials instead of synthetic or chemical drugs is increasing. Herbal materials are found in medicines. Herbs can be used in the form of plant extracts or as their active components. Furthermore, most of the world’s populations used herbal materials due to their strong antimicrobial properties and primary healthcare benefits. For example, herbs are an excellent material to replace nanosilver as an antibiotic and antiviral agent. The use of nanosilver involves an ROS-mediated mechanism that might lead to oxidative stress-related cancer, cytotoxicity, and heart diseases. Oxidative stress further leads to increased ROS production and also delays the cellular processes involved in wound healing. Therefore, existing antibiotic drugs can be replaced with biomaterials such as herbal medicine with high antimicrobial, antiviral, and antioxidant activity. This review paper highlights the antibacterial, antiviral, and radical scavenger (antioxidant) properties of herbal materials. Antimicrobial activity, radical scavenger ability, the potential for antimicrobial, antiviral, and anticancer agents, and efficacy in eliminating bacteria and viruses and scavenging free radicals in herbal materials are discussed in this review. The presented herbal antimicrobial agents in this review include clove, portulaca, tribulus, eryngium, cinnamon, turmeric, ginger, thyme, pennyroyal, mint, fennel, chamomile, burdock, eucalyptus, primrose, lemon balm, mallow, and garlic, which are all summarized.

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Section: Antimicrobial Agentmentioning

confidence: 99%

Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials

et al. 2020

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“…Ambas as variáveis revelaram efeitos positivos, por exemplo, aumentando a razão mássica e a temperatura, o rendimento de extração aumenta consequentemente. Isso corrobora com achados anteriores da literatura de Cruz et al [15], Mazzutti et al [16], Fetzer et al [17] e Rodriguez et al [18] para diferentes matérias primas.…”

Section: Rendimentos De Extração (X 0 )unclassified

RENDIMENTO E MODELAGEM MATEMÁTICA DA EXTRAÇÃO USANDO CO2 SUPERCRÍTICO + ETANOL DE FOLHAS DE YACON (Smallanthus sonchifolius)

Cruz¹,

Fetzer²,

Amaral³

et al. 2020

Anais Do SIMPROC

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Este estudo apresenta as extrações de folhas de yacon usando fluido supercrítico CO 2 + etanol (scCO 2 +EtOH). Ensaios foram realizados sob as seguintes condições: 30-70 ºC, 15-25 MPa e variando a razão mássica de etanol (co-solvente) para sólido (matéria prima) RM. Todas as extrações foram avaliadas em termos de rendimento total de extração (X 0) e as cinéticas de extração foram apresentadas. Os extratos foram obtidos satisfatoriamente usando a tecnologia supercrítica. O rendimento variou de 2,32 % usando scCO 2 +EtOH a 30ºC/ 25 MPa/ RM 1:1 até 5,22 % a 70 ºC/ 25 MPa/ RM 3:1.

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“…The two extracts showed different antioxidant capacity evaluated by FRAP (15.2 ± 2.2 and 58.7 ± 1.2 μmol TE per g, for Hex and EtOH extract, respectively), DPPH (22.8 ± 7.3 and 72.8 ± 1.2%, for Hex and EtOH extract, respectively), and ORAC (867.9 ± 36.6 and 926.9 ± 48.3 μmol TE per g, for Hex and EtOH extract, respectively; Franco et al, ), suggesting that EtOH is more effective for extraction of bioactive compounds with a marked antioxidant activity. Moreover, Rodriguez et al () demonstrated that supercritical extraction using CO 2 as solvent and MeOH as co‐solvent is effective to obtain an extract with a high antioxidant activity, evaluated by using DPPH (IC 50 : 0.13 mg/ml).…”

Section: The Role Of a Lappa In Contrasting The Oxidative Stressmentioning

confidence: 99%

Arctium lappa contributes to the management of type 2 diabetes mellitus by regulating glucose homeostasis and improving oxidative stress: A critical review of in vitro and in vivo animal‐based studies

Annunziata

Barrea²,

Ciampaglia

et al. 2019

Phytotherapy Research

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Diabetes is a metabolic disease highly widespread worldwide, and the most common form is the type 2 diabetes mellitus (T2DM). A large number of synthetic drugs are currently available for the treatment of diabetes; however, they present various side effects and, for this reason, people are increasingly inclined to search natural alternative treatments. Among these, Arctium lappa (A. lappa) has interesting anti‐diabetic activities, exerted by improving glucose homeostasis and reducing insulin‐resistance. In addition, A. lappa exerts a marked antioxidant activity, an effect known to play a pivotal role in the treatment of T2DM. The purpose of this review is to analyse scientific evidence in order to evaluate the role of A. lappa and its bioactive compounds in management of T2DM. The literature search performed provided only in vitro and animal‐based studies. No clinical studies have been conducted in order to investigate the effect of A. lappa on T2DM patients. However, available literature provides evidence for further clinical trials in order to confirm these claimed activities on humans.

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Kinetics, composition and antioxidant activity of burdock (Arctium lappa) root extracts obtained with supercritical CO2 and co-solvent

Cited by 38 publications

References 57 publications

Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials

Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials

RENDIMENTO E MODELAGEM MATEMÁTICA DA EXTRAÇÃO USANDO CO2 SUPERCRÍTICO + ETANOL DE FOLHAS DE YACON (Smallanthus sonchifolius)

Arctium lappa contributes to the management of type 2 diabetes mellitus by regulating glucose homeostasis and improving oxidative stress: A critical review of in vitro and in vivo animal‐based studies

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