KNOWLEDGE Of ANTIBIOTIC USE, MISUSE AND ANTIBIOTIC RESISTANCE IN THE SLUM COMMUNITY IN KARACHI

Abstract

Background: Worldwide antimicrobial resistance is hugely increasing in the response of inappropriate antibiotic use. Our objectives were to assess knowledge of antibiotic use, misuse and antibiotic resistance in the slum community of Karachi. Methods: This Community-based cross-sectional study was carried out Shireen Jinnah Colony in Karachi for the period of six months from 1st January to 30th June 2017.Subjects of both genders were approached through convenient non-probability sampling technique. Subjects of both genders having age 15 years and above and who were willing to participate in the study were included. An adapted and validated questionnaire was used for data collection. Results: Out of total 120 subjects, the majority of 100 (83.3%) were males, 64 (53.3%) married, 36 (30%) were matriculate and 54.2% fell in the age group between 15-30 years of age. Majority of 77.5% participants never attended any seminar or workshop about antibiotic resistance. Most of 73.33% subjects answered that antibiotics are effective in treating both bacterial and viral infections. 60.83% of respondents purchase antibiotic with the prescription. 70 % of subjects knew about antibiotic adverse drug reaction. In addition, 60.83% stop the antibiotic medication when feeling better. Conclusion: The study concluded the lack of knowledge of the use of antibiotics and the unnecessary and improper use of the antibiotic may cause antibiotic resistance.

<p>Knowledge and Attitude Towards Antimicrobial Resistance of Graduating Health Science Students of Wollega University</p>

“…22 As it is a condition for which a bacterium loses its response towards an antimicrobial, 86.6% agreed that antibiotic misuse leads to resistance and 67.7% agreed on taking a full course of antibiotic treatment irrespective of symptomatic improvement to prevent the development of antimicrobial resistance. This is comparable with the study findings from Nigeria (63.3%), Pakistan (62.5%), and India (54.5%).- 21,23,24 However, it is low compared to the study done in Italy where more than 90% of respondents were agreed that misuse leads to resistance (98%), a full course of treatment is mandatory despite symptoms improving (94.8%), and who knew that antibiotic resistance can occur when the bacteria lose sensitivity to the agent (93.9%). The discrepancies could have resulted from the fact that in developed nations, students can get access to health information even before formal academic education from different sources, which is less likely in developing countries like Ethiopia.…”

Drivers of household antibiotic use in urban informal settlements in Northern Ghana: Implications for antimicrobial resistance control

“…Several factors have been associated with knowledge of antibiotic use and resistance 4,15,17,27,31 . In this study, respondents with higher levels of education, and wealthy households were more likely to have good knowledge than the uneducated ones.…”

“…In Ghana, the availability of a wide range of antibiotics in the open market, 1,26 the extensive OTC dispensing of drugs, 26 and the financial gains of medicine sellers propel the community demand for antibiotics. Access to antibiotics without prescription is common in many LMICs 1,2,4,17,18,26,27 . This has resulted in the indiscriminate use of antibiotics and its associated rise in antibiotic resistance in such countries 4,5 …”

“…Access to antibiotics without prescription is common in many LMICs. 1 , 2 , 4 , 17 , 18 , 26 , 27 This has resulted in the indiscriminate use of antibiotics and its associated rise in antibiotic resistance in such countries. 4 , 5 …”

“…Access to antibiotics without prescription is common in many LMICs. 1,2,4,17,18,26,27 This has resulted in the indiscriminate use of antibiotics and its associated rise in antibiotic resistance in such countries. 4,5 Antibiotic use without prescription (self-medication) was associated with older respondents, those with higher educational levels, low MHI, larger households, and poor knowledge.…”