Korneale Aberrationen vor und nach kornealer und korneoskleraler Kleinschnitt-Katarakt-Chirurgie

Kißner, A.; Kohlhaas, M.; Spörl, E.; Pillunat, Lutz E

doi:10.1055/s-2006-927390

Cited by 6 publications

(3 citation statements)

References 14 publications

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“…A possible explanation for this pattern observed in our study may be the revival of the corneal nerves. The clear corneal incisions made during cataract surgery can lower the sensitivity [ 3 ]. On postoperative healing, new neurite cells appear and neural growth factors are released to regenerate the corneal axon [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

“…The exacerbation of dry eye after cataract surgery is possibly multifactorial. The reduced corneal sensitivity due to the transection of the corneal nerves [ 3 ], phototoxic damage from an exposure to the microscopic light [ 4 ], multiple irrigations of the corneal epithelium during operation [ 5 ], elevation of inflammatory cytokines in the lacrimal tear [ 6 ], and the use of topical anesthesia and antibiotics during surgery in addition to preservative containing topical eye drops administered after surgery [ 7 ] would influence dry eye following cataract surgery, but how these factors influence dry eye after cataract surgery is unclear. Kim et al reported benzalkonium chloride induces tear film instability and ocular surface damage in a dose dependent manner [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

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Observation of Influence of Cataract Surgery on the Ocular Surface

2016

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IntroductionTo evaluate meibomian gland function, changes of lacrimal tears and ocular surface parameters and tear inflammatory mediators following cataract surgery.Methods48 eyes of 34 patients who underwent uncomplicated phacoemulsification were involved and divided into 2 groups with those who had preexisting dry-eye before cataract surgery and those who did not. Ocular symptom score, Schirmer I test, tear film break-up time (TBUT), corneal sensitivity threshold, corneal staining, inflammatory cytokine activities, lid margin abnormalities, meibum expressibility, meibum quality and meibomian gland imaging were evaluated preoperatively, at 1 day, 1 and 2 months postoperatively.ResultsOcular symptom scores were worse at 1 and 2 months postoperatively but, TBUT, corneal staining score and corneal sensitivity threshold showed gradual improvements at 1 month and 2 months postoperatively (p<0.05, respectively). Interestingly there were statistically significant improvements in TBUT, corneal staining score and corneal sensitivity threshold at 1 month postoperatively when topical eye drops were used compared to the period without topical therapy which is the months 2 postoperatively. There were statistically significant decreases in IL-1β, IL-6, IL-8, MCP-1, TNF-α and IFN-γ concentrations at 1 and 2 months postoperatively. Lid margin abnormalities, meibum quality and expressibility scores increased significantly (p < 0.05, respectively) at postoperative period. Compared with the no dry eye group, dry eye group revealed significantly higher ocular symptom scores, lower TBUT, higher lid margin abnormalities, meibum quality and expressibility scores after cataract surgery. There were significant correlations between IL-6 and parameters of dry eye, and between MGD parameters and ocular symptom scores.ConclusionsOur study revealed that meibomian gland function is influenced after cataract surgery accompanying structural changes and these were correlated with increased ocular symptom scores. Therefore, it could elucidate the development of dry eye related to cataract surgery.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Observation of Influence of Cataract Surgery on the Ocular Surface

2016

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“…The onset or the exacerbation of dry eye after cataract surgery is related to a multifactorial process. Corneal sensitivity is reduced by the interruption of the corneal nerves,5 a phototoxic damage derives from the exposure to the microscopic light,6 corneal irrigation may damage the epithelium,7 and inflammatory cytokines elevation in the lacrimal tear have also been demonstrated 8. Finally, the use of topical anesthesia and preservative containing topical eye drops administered after surgery would also have a role in patient ocular surface discomfort 9.…”

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confidence: 99%

<p>Efficacy of carbomer sodium hyaluronate trehalose vs hyaluronic acid to improve tear film instability and ocular surface discomfort after cataract surgery</p>

Caretti¹,

Valerio²,

Piermarocchi³

et al. 2019

OPTH

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Purpose To evaluate the effects of carbomer sodium hyaluronate trehalose (CHT) and sodium hyaluronate eye drops on tear film stability and ocular discomfort after cataract surgery. Setting Santa Maria della Misericordia Hospital, Rovigo, Italy. Design Prospective randomized case-control study. Patients and methods This study enrolled sixty patients scheduled for unilateral cataract surgery. After phacoemulsification, subjects received carbomer sodium hyaluronate trehalose (trehalose group) or sodium hyaluronate tears (HG group) substitute and were assessed through objective (break up time, corneal and conjunctival staining) and subjective (OSDI questionnaire) clinical evaluations after a two times a day topical administration. Outcome measures were collected preoperatively (baseline), one week (day 7) and 1 month (day 30) after surgery. Finally, each patient was asked to give his personal treatment satisfaction score. Results Trehalose group showed a steeper break up time (BUT) increase compared to patient treated with hyaluronic acid ( P <0.001). OSDI questionnaire presented a opposite trend, trehalose patients evidenced a significantly major improvement ( P <0.001), and in seven days mean values reduced by more than three times. Fluorescein staining reduction was documented with both treatments, although there was no statistically significant difference between groups. Finally CHT resulted in a significantly greater global satisfaction score ( P <0.001). Conclusions CHT was effective and well tolerated in reducing dry eye disease symptoms and improving the clinical outcome after cataract surgery. On some parameters (BUT, OSDI), this new formulation was more effective than commonly used sodium hyaluronate in treating ocular irritation and tear film alterations.

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Central corneal epithelial thickness changes after half-moon supracapsular nucleofractis phacoemulsification technique

et al. 2017

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Korneale Aberrationen vor und nach kornealer und korneoskleraler Kleinschnitt-Katarakt-Chirurgie

Abstract: In accordance with the induced higher-order aberrations both surgical techniques can be considered as being equivalent.

Cited by 6 publications

References 14 publications

Observation of Influence of Cataract Surgery on the Ocular Surface

Observation of Influence of Cataract Surgery on the Ocular Surface

<p>Efficacy of carbomer sodium hyaluronate trehalose vs hyaluronic acid to improve tear film instability and ocular surface discomfort after cataract surgery</p>

Central corneal epithelial thickness changes after half-moon supracapsular nucleofractis phacoemulsification technique

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