Kostanecki‐Robinson Reaction

Abstract

The formation of coumarins and chromones from alkyl o ‐hydroxyaryl ketone and aliphatic acid anhydride in the presence of the corresponding aliphatic acid sodium salt, via the O ‐acylation and aldol condensation is generally known as the Kostanecki–Robinson reaction. It has been reported that depending on the actual reaction conditions and substituents, either coumarin or chromone or both can be produced. The existing α‐pyrone ring on the aromatic ketone does not affect the reaction.