L’adénomyose : le point sur une pathologie méconnue

Wéry, O.; Thille, Alain; Gaspard, Ulysse; Brûle, Frédéric van den

doi:10.1016/s0368-2315(05)82896-0

Cited by 10 publications

(3 citation statements)

References 202 publications

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“…In the past, a diagnosis of AM is often established only at histological examination of uterus, limiting the rate of AM to patients who received hysterectomy. According to pathological reports, the incidence of AM ranges from 5 to 70%, depending on the histological criteria and the number of sections examined (2,27,28). Due to the risks of surgery in AM patients, it is difficult to completely remove the lesions for conservative surgery.…”

Section: Discussionmentioning

confidence: 99%

Clinical Features and Long-Term Outcomes After Laparoscopic Surgery in Patients Co-existing With Endometriosis and Adenomyosis

Sun

Shi

et al. 2021

Front. Med.

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Objective: To investigate the difference of clinical features and outcomes between EM patients with and without AM after following up for at least 6 years after surgery.Methods: We retrospectively analyzed 358 EM patients who had a minimum of 6 years follow-up after laparoscopic cystectomy, which was performed by one single doctor at Peking Union Medical College Hospital from January 2009 to April 2013. All women were divided into AM group and non-AM group and analysis was performed in preoperative characteristics, surgical findings and postoperative outcomes during follow-up.Results: A total of 358 EM patients were recruited, of which 142 (39.7%) were in the AM group and the rest 216 (60.3%) in the non-AM group. Between the two group, the mean age was 34.6 vs. 32.2 years (P < 0.001). The mean operating time in the AM and non-AM group was 73.2 vs. 61.9 min (P < 0.001). According to the revised AFS classification, the mean score of the two group were 60.3 vs. 45.5 (P < 0.001). At the end of the follow-up, though the AM group was with higher rate of disease relapse, yet no significant difference was found between the two groups in statistical comparison (34/142 [23.9%] vs. 34/216 [15.7%], P = 0.053). With a minimum follow-up of 6 years after laparoscopic cystectomy, failed and successful pregnancy were seen in 107/142(75.4%) and 35/142 (24.6%) patients in the AM group vs. 114/216(52.8%) and 102/216 (47.2%) patients in the non-AM group (P < 0.05). As for the successfully pregnant patients, live births, including spontaneous pregnancy and IVF-ET, were seen in 34/35 (97.1) vs. 99/102 (97.1) patients between AM and non-AM groups, while others ended in spontaneous abortion. No significant associations were found between the two groups in infertility, leiomyoma presence, the size of ovarian endometrioma, type of deep infiltrating endometriosis (DIE) or type of recurrence (P > 0.05).Conclusion: Compared with non-AM group, EM patients with concurrent AM may have higher age, longer mean operating time and higher mean AFS score. In terms of fertility outcomes, patients in the AM group were with lower likelihood of pregnancy after surgery during the long-time follow-up.

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Section: Discussionmentioning

confidence: 99%

Clinical Features and Long-Term Outcomes After Laparoscopic Surgery in Patients Co-existing With Endometriosis and Adenomyosis

Sun

Shi

et al. 2021

Front. Med.

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“…A ultra-sonografia transvaginal apresenta sensibilidade que varia de 46 a 100% para o diagnóstico da adenomiose, segundo revisão da literatura realizada por Levgur (2007). Sua especificidade varia de 50 a 100% (Wéry et al, 2005). Diversas alterações à ultra-sonografia são descritas como sugestivas de adenomiose.…”

Section: Diagnóstico De Adenomiose Na Paciente Infértilunclassified

The adenomyosis impact on infertility

Santos¹,

Crispi²

2009

JBRA

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A adenomiose é uma doença relacionada à presença de glândulas e estroma endometrial na musculatura uterina, em profundidade e extensão variáveis. Sua incidência é estimada em torno de 20% a 30%. O diagnóstico de adenomiose tem como padrão-ouro o estudo histopatológico do útero pós-histerectomia. Dentre os métodos nãoinvasivos, a ressonância nuclear magnética apresenta a melhor acurácia. Dismenorréia e menorragia são os principais sintomas relacionados à adenomiose. Há evidências que a adenomiose possa atuar como um fator gerador de infertilidade feminina, associada ou não à presença de endometriose. Os mecanismos atribuídos à adenomiose e relacionados à infertilidade são pouco esclarecidos. Segundo a literatura consultada, o principal fator envolvido é a interferência da disperistalse ou hiperperistalse uterina no transporte espermático. Fatores imunológicos e falha na implantação embrionária são citados, apesar de estudos recentes sugerirem que as taxas de implantação em ciclos de fertilização in vitro não são modificadas na presença de adenomiose.

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“…L'adénomyose est fréquemment associée à d'autres pathologies dont l'hyperplasie endométriale simple ou atyTableau 1 Principales études concernant la fréquence de l'adénomyose pique, les polypes endométriaux, les fibromyomes et l'endométriose [4][5][6][7][8][9][10]. La contraception par stérilet au cuivre ou par pilule estroprogestative ne sont pas des facteurs de risques d'adénomyose.…”

Section: Facteurs De Risquesunclassified

Adénomyose

Fernandez

Donnadieu

2007

Journal de Gynécologie Obstétrique et Biologie de la Reproducti

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Diagnostic adenomyosis is done by pathologist (grade A). Adenomyosis is usually asymptomatic (grade C). Symptomatic adenomyosis gives pains and/or bleedings (grade C). Hysterosalpingography is not included in diagnostic strategy (grade B). Sonography has a good sensitivity and can be exclusively used for therapeutic strategy (grade B). MRI is pertinent but only useful in case of associated lesions (grade B). Hysterectomy is the gold standard for symptomatic patients without desire of pregnancy (grade B). Medical treatments are: IUD with levonorgestrel, Gn-RH analog, antigonadotrope progestin (grade C). Uterine artery embolisation is not recommended (professional agreement). Endometrial resection/destruction are indicated in case of menorraghia (grade C).

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L’adénomyose : le point sur une pathologie méconnue

Cited by 10 publications

References 202 publications

Clinical Features and Long-Term Outcomes After Laparoscopic Surgery in Patients Co-existing With Endometriosis and Adenomyosis

Clinical Features and Long-Term Outcomes After Laparoscopic Surgery in Patients Co-existing With Endometriosis and Adenomyosis

The adenomyosis impact on infertility

Adénomyose

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