L-serine improves lipid profile, performance, carcass weight and intestinal parameters in feed restricted broiler chickens during the hot-dry season

Ogbuagu, Ngozi Ejum; Ayo, Joseph Olusegun; Aluwong, Tagang; Akor-Dewu, Maryam Baraka

doi:10.1007/s11250-022-03318-0

Cited by 6 publications

(2 citation statements)

References 57 publications

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“…In this study, dietary supplementation with serine alone increased IMF content, further suggesting that serine may positively affect IMF deposition. Previous studies have demonstrated the role of serine in lipid metabolism [21], and serine deficiency increases fat deposition in the liver [12]. Serine participates critically in onecarbon metabolism and promotes NADPH synthesis, which is involved in the regulation of lipid metabolism [22].…”

Section: Discussionmentioning

confidence: 99%

Dietary Serine Supplementation Improves Growth Performance, Intramuscular Fat Content, and Composition of Gut Microbes and Metabolites in Growing–Finishing Pigs

Guo,

He,

Deng

et al. 2024

Agriculture

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Serine is widely involved in antioxidant synthesis, immune response, and fat metabolism. However, it remains unclear whether dietary serine supplementation affects fat deposition in the skeletal muscles of pigs. Thus, we explored the effects of dietary serine supplementation on growth performance, meat quality, and composition of gut microbes and their metabolites in growing–finishing pigs. Forty-eight boars weighing approximately 20 kg were fed either a basal diet or a basal diet supplemented with 0.15% serine. The results showed that dietary serine increased the daily weight gain of pigs and improved serum antioxidant capacity as indicated by the decreased malondialdehyde content and increased glutathione and superoxide dismutase content. Pigs supplemented with serine had better meat quality, as shown by the lower drip loss and higher IMF content. Furthermore, dietary serine increased the relative abundance of Streptococcus and Lactobacillus and decreased the relative abundance of Clostridium_sensu_stricto_1 and Terrisporobacter. Differential microbial metabolites were mostly enriched in metabolic pathways related to lipid synthesis, such as alpha-linolenic acid metabolism and steroid hormone biosynthesis. Correlation analysis showed that the altered metabolites were closely related to the intestinal microbiota. In conclusion, our results suggested that serine serves as a potential additive for improving IMF content in growing–finishing pigs.

show abstract

Section: Discussionmentioning

confidence: 99%

Dietary Serine Supplementation Improves Growth Performance, Intramuscular Fat Content, and Composition of Gut Microbes and Metabolites in Growing–Finishing Pigs

Guo,

He,

Deng

et al. 2024

Agriculture

View full text Add to dashboard Cite

show abstract

“…In this study, dietary supplementation with serine alone increased IMF content, further suggesting that serine may positively affect IMF deposition. Previous studies have demonstrated the role of serine in lipid metabolism [23], and serine deficiency increases fat deposition in the liver [14]. Serine participates critically in one-carbon metabolism and promotes NADPH synthesis, which is involved in the regulation of lipid metabolism [24].…”

Section: Discussionmentioning

confidence: 99%

Dietary Serine Supplementation Improves Growth Performance, Meat Quality, and Composition of Gut Microbes and Metabolites in Growing‐Finishing Pigs

Yiting,

Fang,

Zhiying

et al. 2023

Preprint

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Serine is widely involved in antioxidant synthesis, immune response, and fat metabolism. However, it remains unclear whether dietary serine supplementation affects fat deposition in the skeletal muscles of pigs. Thus, we explored the effects of dietary serine supplementation on growth performance, meat quality, and composition of gut microbes and their metabolites in growing-finishing pigs. Forty-eight boars weighing approximately 20 kg were fed either a basal diet or a basal diet supplemented with 0.15% serine. The results showed that dietary serine increased the daily weight gain and improved the antioxidant ability of pigs, as indicated by the decreased malondialdehyde content and increased glutathione and superoxide dismutase content. Pigs supplemented with serine had better meat quality, as shown by the lower drip loss and higher IMF content. Furthermore, dietary serine increased the relative abundance of Streptococcus and Lactobacillus and decreased the relative abundance of Clostridium_sensu_stricto_1 and Terrisporobacter. Differential microbial metabolites were mostly enriched in metabolic pathways related to lipid synthesis, such as alpha-linolenic acid metabolism and steroid hormone biosynthesis. Correlation analysis showed that the altered metabolites were closely related to the intestinal microbiota. In conclusion, our results suggested that serine serves as a potential additive for improving meat quality in growing-finishing pigs.

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Serine metabolism in aging and age-related diseases

Shan,

Hoffman

2024

GeroScience

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L-serine improves lipid profile, performance, carcass weight and intestinal parameters in feed restricted broiler chickens during the hot-dry season

Cited by 6 publications

References 57 publications

Dietary Serine Supplementation Improves Growth Performance, Intramuscular Fat Content, and Composition of Gut Microbes and Metabolites in Growing–Finishing Pigs

Dietary Serine Supplementation Improves Growth Performance, Intramuscular Fat Content, and Composition of Gut Microbes and Metabolites in Growing–Finishing Pigs

Dietary Serine Supplementation Improves Growth Performance, Meat Quality, and Composition of Gut Microbes and Metabolites in Growing‐Finishing Pigs

Serine metabolism in aging and age-related diseases

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