La
                  0.7
                  Sr
                  0.3
                Mn
                  O
                  3
           nanoparticles coated with fatty amine

Rajagopal, Rajashree; Mona, J.; Kale, S. N.; Bala, Tanushree; Pasricha, Renu; Poddar, Pankaj; Sastry, Murali; Prasad, B. L. V.; Kundaliya, Darshan C.; Ogale, S. B.

doi:10.1063/1.2210080

Cited by 37 publications

(24 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The lower saturation moment of Dex-LSMO could be attributed to their smaller size and the influence of coating on magnetization of the nanoparticles. Such magnetization drops have been reported after coating of LSMO with octadecylamine 30 or coating of iron oxide nanoparticles with silica. 31 Hysteresis loops (inset to Figure 5) revealed that LSMO and Dex-LSMO were predominantly ferromagnetic at room temperature.…”

Section: Vibrating Sample Magnetometrymentioning

confidence: 97%

Temperature-dependent and time-dependent effects of hyperthermia mediated by dextran-coated La0.7Sr0.3MnO3: in vitro studies

Haghniaz¹,

Umrani²,

Paknikar³

2015

IJN

View full text Add to dashboard Cite

Background The purpose of this study was to investigate the therapeutic efficacy of dextran-coated (Dex) La 0.7 Sr 0.3 MnO 3 (LSMO) nanoparticles-mediated hyperthermia at different temperatures (43°C, 45°C, and 47°C) based on cell killing potential and induction of heat shock proteins in a murine melanoma cell (B16F1) line. Methods LSMO nanoparticles were synthesized by a citrate-gel method and coated with dextran. B16F1 cells were exposed to the Dex-LSMO nanoparticles and heated using a radiofrequency generator. After heating, the morphology and topology of the cells were investigated by optical microscopy and atomic force microscopy. At 0 hours and 24 hours post heating, cells were harvested and viability was analyzed by the Trypan blue dye exclusion method. Apoptosis and DNA fragmentation were assessed by terminal deoxynucleotidyl transferase-dUTP nick end labeling (TUNEL) assay and agarose gel electrophoresis, respectively. An enzyme-linked immunosorbent assay was used to quantify heat shock protein levels. Results Our data indicate that cell death and induction of heat shock proteins in melanoma cells increased in a time-dependent and temperature-dependent manner, particularly at temperatures higher than 43°C. The mode of cell death was found to be apoptotic, as evident by DNA fragmentation and TUNEL signal. A minimum temperature of 45°C was required to irreversibly alter cell morphology, significantly reduce cell viability, and result in 98% apoptosis. Repeated cycles of hyperthermia could induce higher levels of heat shock proteins (more favorable for antitumor activity) when compared with a single cycle. Conclusion Our findings indicate a potential use for Dex-LSMO-mediated hyperthermia in the treatment of melanoma and other types of cancer.

show abstract

Section: Vibrating Sample Magnetometrymentioning

confidence: 97%

Temperature-dependent and time-dependent effects of hyperthermia mediated by dextran-coated La0.7Sr0.3MnO3: in vitro studies

Haghniaz¹,

Umrani²,

Paknikar³

2015

IJN

View full text Add to dashboard Cite

show abstract

“…It should be noted that only some physical properties of nanopowdered La 0.7 Sr 0.3 MnO 3 (LSMO) manganites were studied in a few papers [4][5][6][7][8]. The nanocrystallites were shown to exhibit properties that are significantly different from those of the bulk material.…”

Section: Introductionmentioning

confidence: 96%

Magnetic, resonance and transport properties of nanopowder of La0.7Sr0.3MnO3 manganites

Dyakonov

Ślawska‐Waniewska

Nedelko

et al. 2010

Journal of Magnetism and Magnetic Materials

View full text Add to dashboard Cite

“…Although this article does not include a study of toxicity, we will note some essential points. Many experiments on the coating La–Sr manganites with biocompatible shells including SiO 2 , dextran, citrate ligands, fatty amines, polyvinylpyrrolidone (PVP), etc. proved the colloidal stability and biocompatibility of LSMO NPs.…”

Section: Numerical Results and Discussionmentioning

confidence: 99%

La_1−xSr_xMnO₃ Nanoparticles for Magnetic Hyperthermia

Apostolov

Apostolova

Wesselinowa

2018

Physica Status Solidi (b)

View full text Add to dashboard Cite

Using a modified Heisenberg model and a Green's function technique we have studied the influence of size d and concentration x of Sr dopants on the Curie temperature T C , saturation magnetization M S , coercivity H C and specific absorption rate (SAR) of single-domain La 1Àx Sr x MnO 3 nanoparticles. Their magnetic properties are explained based on the "magnetically death" surface layer and the competition between the ferromagnetic double-exchange and antiferromagnetic super-exchange interaction. We calculated the specific absorption rate which characterizes the efficiency of the absorption energy when the magnetic hyperthermia is applied as a therapeutic method for the treatment of tumors. A set of nanoparticles appropriate for in vivo and in vitro medical applications, such as magnetic hyperthermia and drug delivery to cancer cells, is determined. The established methodology and microscopic model are suitable to study the magnetic properties of low-dimensional systems (thin films and nanoparticles) such as La 1Àx A x MnO 3 with A ¼ Ca, Ag, Ba, Na for medical applications.

show abstract

La 0.7 Sr 0.3 Mn O 3 nanoparticles coated with fatty amine

Cited by 37 publications

References 26 publications

Temperature-dependent and time-dependent effects of hyperthermia mediated by dextran-coated La0.7Sr0.3MnO3: in vitro studies

Temperature-dependent and time-dependent effects of hyperthermia mediated by dextran-coated La0.7Sr0.3MnO3: in vitro studies

Magnetic, resonance and transport properties of nanopowder of La0.7Sr0.3MnO3 manganites

La_1−xSr_xMnO₃ Nanoparticles for Magnetic Hyperthermia

Contact Info

Product

Resources

About

La 0.7 Sr 0.3 Mn O 3 nanoparticles coated with fatty amine

Cited by 37 publications

References 26 publications

Temperature-dependent and time-dependent effects of hyperthermia mediated by dextran-coated La0.7Sr0.3MnO3: in vitro studies

Temperature-dependent and time-dependent effects of hyperthermia mediated by dextran-coated La0.7Sr0.3MnO3: in vitro studies

Magnetic, resonance and transport properties of nanopowder of La0.7Sr0.3MnO3 manganites

La1−xSrxMnO3 Nanoparticles for Magnetic Hyperthermia

Contact Info

Product

Resources

About

La_1−xSr_xMnO₃ Nanoparticles for Magnetic Hyperthermia