The introduction examines the discourses of health that Latinx cultural workers engage in their work. First, it elaborates how Latinx artists conceptualize health within a sociopolitical landscape shaped by the Immigration Reform and Control Act, the Americans with Disabilities Act, the Personal Responsibility and Work Opportunity Reconciliation Act, and the Affordable Care Act. Second, it outlines the methodology of interdisciplinary literary study and the engagement with disability studies and the health humanities that guide the project. In order to demonstrate the kind of cultural studies analysis that the book undertakes, the introduction examines the debates surrounding the passage and implementation of the Affordable Care Act and the performance manifesto Your Healing Is Killing Me by artist Virginia Grise. Finally, it elaborates a definition of radical health, which involves both challenging the stigma of unhealth and protesting the social conditions that give rise to racial health disparities.