Label-free biosensing using a nanostructured Fabry-Perot interferometer

Zhang, Tianhua; Karandikar, Sukrut; Gong, Zhongcheng; Giorno, Rebecca; Que, Long

doi:10.1109/icsens.2010.5690317

Cited by 2 publications

(2 citation statements)

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“…A FPI is highly sensitive with respect to geometric properties for which small changes can be measured [ 59 , 60 ]. The main advancement in the Fabry-Perot setup is a nanostructured FPI, which is more sensitive than a conventional FPI configuration [ 61 ]. The basic principles of operation of the device are shown in Figure 3a .…”

Section: Introduction To Interferometrymentioning

confidence: 99%

“…First, a beamsplitter is used to split light from a light source into two components, which are recombined by a second beamsplitter. The relative phase difference is measured by the beam along the two paths, and the second beamsplitter will display the beam with an efficiency varying from 0% to 100% [ 61 ]. This device can be further miniaturized with integrated optics for the scheme shown in Figure 3b .…”

Section: Introduction To Interferometrymentioning

confidence: 99%

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Development of Phase Detection Schemes Based on Surface Plasmon Resonance Using Interferometry

Kashif

Bakar

Arsad

et al. 2014

Sensors

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Surface plasmon resonance (SPR) is a novel optical sensing technique with a unique ability to monitor molecular binding in real-time for biological and chemical sensor applications. Interferometry is an excellent tool for accurate measurement of SPR changes, the measurement and comparison is made for the sensitivity, dynamic range and resolution of the different analytes using interferometry techniques. SPR interferometry can also employ phase detection in addition to the amplitude of the reflected light wave, and the phase changes more rapidly compared with other approaches, i.e., intensity, angle and wavelength. Therefore, the SPR phase interferometer offers the advantages of spatial phase resolution and high sensitivity. This work discusses the advancements in interferometric SPR methods to measure the phase shifts due to refractive index changes. The main application areas of SPR sensors are demonstrated, i.e., the Fabry-Perot interferometer, Michelson interferometer and Mach-Zehnder interferometer, with different configurations. The three interferometers are discussed in detail, and solutions are suggested to enhance the performance parameters that will aid in future biological and chemical sensors.

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Section: Introduction To Interferometrymentioning

confidence: 99%

Section: Introduction To Interferometrymentioning

confidence: 99%