Label-free biosensor for viruses and bacteria detection

Aznakayev, E. G.; Aznakayeva, D. E.

doi:10.1117/12.2572685

Cited by 1 publication

(1 citation statement)

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“…While the target in the second approach is viral antigens like its surface proteins and the probe is the antibodies against them. The third approach targets the viral genomic material utilizing its complementary nucleotides and the fourth is designed to capture the antibodies produced in the host body as a response to the virus employing the matching antigens as BREs [89][90][91]. Overall, the sensing scheme is founded on measuring the electrical characteristics of the GFET's gate after the occurrence of biological reactions [86].…”

Section: A Virusmentioning

confidence: 99%

Laser-Induced Graphene-Functionalized Field-Effect Transistor-Based Biosensing: A Potent Candidate for COVID-19 Detection

Sadighbayan

Minhas-Khan

Ghafar-Zadeh

2022

IEEE Trans.on Nanobioscience

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Speedy and on-time detection of coronavirus disease 2019 (COVID-19) is of high importance to control the pandemic effectively and stop its disastrous consequences. A widely available, reliable, label-free, and rapid test that can recognize tiny amounts of specific biomarkers might be the solution. Nanobiosensors are one of the most attractive candidates for this purpose. Integration of graphene with biosensing devices shifts the performance of these systems to an incomparable level. Between the various arrangements using this wonder material, field-effect transistors (FETs) display a precise detection even in complex samples. The emergence of pioneering biosensors for detecting a wide range of diseases especially COVID-19 created the incentive to prepare a review of the recent graphene-FET biosensing platforms. However, the graphene fabrication and transfer to the surface of the device is an imperative factor for researchers to take into account. Therefore, we also reviewed the common methods of manufacturing graphene for biosensing applications and discuss their advantages and disadvantages. One of the most recent synthesizing techniques -laser-induced graphene (LIG)is attracting attention owing to its extraordinary benefits which are thoroughly explained in this article. Finally, a conclusion highlighting the current challenges is presented.

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