Lack of coagulation defects after the intraamniotic instillation of ethacridine (Rivanol) for second trimester abortion

Abstract

Second trimester abortion was induced by the intraamniotic infusion of ethacridine. Coagulation studies revealed no change in 10 cases. It is felt that the intraamniotic use of ethacridine is probably safe.

Induction of second trimester abortion by intraamniotic instillation of rivanol (ethacridine) combined with oxytocin infusion

“…The technique is simple, there are no side-effects, and because Rivanol has antiseptic properties the incidence of infection is low. Neither extraamniotic nor intraamniotic instillation causes coagulopathy [1], and so the risk of hemorrhage is not increased.…”