Lactating adenoma: US features and literature review.

Sumkin, J H; Perrone, A M; Harris, Kassem; Nath, Manju; Amortegui, Antonio J.; Weinstein, Barbara

doi:10.1148/radiology.206.1.9423682

Cited by 82 publications

(37 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, a few tumors can show features that can mislead from a diagnosis of malignancy, such as irregular masses, microlobulated margins, posterior acoustic shadowing, pronounced hypoechogenicity, and structural heteroechogenicity. Some of these confusing patterns may be due to infarction, as occurs in fibroadenomas (12,(67)(68)(69). .…”

Section: Benign Tumors Tumors Closely Related To Pregnancy and Lactationmentioning

confidence: 99%

Radiologic Evaluation of Breast Disorders Related to Pregnancy and Lactation

Sabaté

Clotet²,

Torrubia³

et al. 2007

RadioGraphics

209

204

View full text Add to dashboard Cite

During pregnancy and lactation, the breast can be affected by a variety of specific and unique disorders, including benign disorders closely related to physiologic changes, inflammatory and infectious diseases, juvenile papillomatosis, and benign and malignant tumors. Patients with pregnancy-associated breast carcinoma tend to have more advanced neoplasms at diagnosis and a poorer prognosis due to delayed diagnosis and a more aggressive biologic pattern. Pregnancy-related Burkitt lymphoma characteristically manifests with bilateral and diffuse involvement of the breasts. Fibroadenoma may manifest with growth, infarction, large cysts, prominent ducts, and secretory hyperplasia during pregnancy and lactation. Galactocele is the breast lesion most commonly found during lactation and manifests as either pseudolipoma, a cystic mass with a fat-fluid level, or pseudohamartoma. Tumors and diseases affecting the breasts during pregnancy and lactation are basically the same as those observed in nonpregnant women but may have a different appearance. The sensitivity of mammography in pregnant and lactating women is decreased due to increased parenchymal density. Instead, ultrasonography is the most appropriate radiologic method for evaluating breast masses in this setting and is particularly useful in the diagnosis and treatment of abscesses. Knowledge of the unique entities that are specifically related to pregnancy and lactation and of their radiologic-pathologic appearances can help the radiologist make the correct diagnosis.

show abstract

Section: Benign Tumors Tumors Closely Related To Pregnancy and Lactationmentioning

confidence: 99%

Radiologic Evaluation of Breast Disorders Related to Pregnancy and Lactation

Sabaté

Clotet²,

Torrubia³

et al. 2007

RadioGraphics

209

204

View full text Add to dashboard Cite

show abstract

“…Lactating adenoma most frequently has a benign appearance: a well-defined, macrolobulated, oval, hypoechoic mass. 23 It is a relatively rare benign neoplasm associated with pregnancy and lactation that usually disappears after the cessation of breast-feeding. The smears can be very cellular and discohesive, and the cells may have prominent nucleoli and display some degree of pleomorphism.…”

Section: Discussionmentioning

confidence: 99%

Granulomatous Inflammation of the Breast in a Pregnant Woman

et al. 2001

View full text Add to dashboard Cite

“…Characteristically, lactating adenoma is a solid mass between 1 and 4 cm in diameter, ovoid or macrolobulated, with well defined margins and its long axis parallel to the chest wall 3. It is typically homogeneous and hypoechoic with posterior acoustic enhancement.…”

Section: Discussionmentioning

confidence: 99%

“…It is typically homogeneous and hypoechoic with posterior acoustic enhancement. Hyperechoic fibrous bands coursing through the lesion and a prominent central duct have been described 3. Occasionally, however, indistinct or irregular margins, heterogeneous echotexture, and posterior acoustic shadowing may be present, making the distinction from a malignant mass more difficult 3.…”

Section: Discussionmentioning

confidence: 99%

“…However, once a solid mass is diagnosed, ultrasound cannot be relied upon to distinguish benign from malignant lesion and tissue sampling is usually warranted to avoid delay in diagnosis of breast cancer. Fine needle aspiration cytology has been associated with some false positive and false negative results, particularly in the setting of lactating adenomas 3. Ultrasound guided core biopsy is therefore often necessary for a definitive diagnosis.…”

Section: Q2: What Further Work-up Is Needed To Confirm the Diagnosis mentioning

confidence: 99%

See 1 more Smart Citation

Palpable breast mass in a lactating woman

2001

Postgraduate Medical Journal

View full text Add to dashboard Cite

A complicated case of von Hippel-Lindau diseaseQ1: What family history should be explored in a 17 year old girl with multiple cerebellar haemangioblastomas and why? The development of haemangioblastoma within the central nervous system is a common first manifestation of von Hippel-Lindau disease, which is inherited in an autosomal dominant fashion.1 A careful family history would be expected to reveal similar features of the condition within first/second degree relatives, unless the presenting case represents a sporadic mutation. In this case, there was no such history and subsequent genetic analysis confirmed the diagnosis by revealing a 796C→T nonsense mutation in exon 3 of the von Hippel-Lindau gene.

show abstract

Lactating adenoma: US features and literature review.

Abstract: The US features, although generally benign, are not specific. Tissue sampling with fine-needle aspiration biopsy is recommended. Core biopsy is necessary if a diagnosis cannot be made with the aspirate but is not performed initially because of the possibility of milk fistula formation.

Cited by 82 publications

References 0 publications

Radiologic Evaluation of Breast Disorders Related to Pregnancy and Lactation

Radiologic Evaluation of Breast Disorders Related to Pregnancy and Lactation

Granulomatous Inflammation of the Breast in a Pregnant Woman

Palpable breast mass in a lactating woman

Contact Info

Product

Resources

About