a b s t r a c tThis paper proposed to provide valuable information for integrated water resources management through evaluating the research on the interaction mechanism among land use changes, regional hydrological ecosystem services and human well-being. Firstly, the driving mechanism of land use and land cover changes was introduced in this paper. Secondly, the overview of the interaction mechanism among land use and land cover changes, regional hydrological ecosystem services and human well-being was given. Based on the meta-analysis, land use changes have a profound influence on regional hydrological ecosystem services, and the variation of hydrological ecosystem could benefit or impair human wellbeing. Finally, two suggestions were emphasized for managers or policy makers for the future integrated water resources management: (1) Proper land use makes for the water resource management; (2) Blindly pursuing the provisioning services weakens other services of hydrological ecosystem.