Lanostane triterpenoids from Ganoderma lucidum and their inhibitory effects against FAAH

Li, Dawei; Liu, Min; Leng, Yueqi; Hu, Jinfang; Deng, Sa; Leng, Aijing; Ma, Xiaochi; Wang, Ruo–Yu; Zhou, Jian; Wang, Chao

doi:10.1016/j.phytochem.2022.113339

Cited by 6 publications

(2 citation statements)

References 38 publications

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“…Hence, the augmentation of ganoderic acid concentration may alone be achieved by the optimization of the fermentation process. Nevertheless, the procurement of ganoderic acids is a signi cant obstacle (Hsu et al, 2008;Li et al, 2022;Zhao et al, 2019). In contrast to substrate cultivation, liquid fermentation has emerged as a viable method for the extraction of ganoderma triterpenes.…”

Section: Introductionmentioning

confidence: 99%

Effect of dissolved oxygen regulation on the content of ganoderic acid S and R in mycelium of Ganoderma lucidum in a two-stage culture by oscillatory-stationary culture

Tang,

Liu,

Jiang

et al. 2023

Preprint

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Currently, liquid fermentation is regarded as a feasible method for cultivating thyme as contrast to subentity culture. Nevertheless, the production of ganoderic acid S and R is still rather limited, thus requiring the need for parameter adjustment in the liquid fermentation process. The influence of thype, an oxygen bacterium, on the viability of microorganisms during liquid fermentation is significant. Moreover, liquid ferments can be classified into two distinct categories: oscillating and static. Prior studies have primarily focused on analyzing these two approaches separately, leading to discrepancies in the consistency and concentration of the fluid form and thyme content. Therefore, the primary objective of this study is to enhance the soluble parameter and incorporate both vibrating and static cultivation methods to facilitate the liquid erection of the grass. The experimental findings indicate that the manipulation of dissolved oxygen during the oscillation stage can significantly enhance the growth of Ganoderma lucidum biomass. However, its impact on the levels of ganoderic acids S and R is comparatively less pronounced. The manipulation of dissolved oxygen during the resting stage yielded contrasting outcomes, leading to a substantial increase in the levels of ganoderic acids S and R, while exerting a lower impact on biomass. The findings of this study demonstrated that the growth of G. lucidum primarily occurred during the oscillating culture stage, while the accumulation of ganoderic acid S and R was predominantly observed during the stationary culture stage. This approach introduces a novel concept for the liquid fermentation of G. lucidum, while simultaneously offering valuable insights for the industrial-scale production of ganoderic acid.

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Section: Introductionmentioning

confidence: 99%

Effect of dissolved oxygen regulation on the content of ganoderic acid S and R in mycelium of Ganoderma lucidum in a two-stage culture by oscillatory-stationary culture

Tang,

Liu,

Jiang

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…The ganoderma lucidum spore, which serves as the plant's seed and can boost immunological control, anti-tumor effects, liver protection, and other effects, was a minuscule, ovoid germ cell that was propelled from the fold of the ganoderma [4] , [5] , [6] . The primary secondary metabolites of ganoderma lucidum are ganoderma triterpenoids, which are further broken down into ganoderma acid, ganoderma alcohol, ganoderma aldehyde, and ganoderma lucidum lactone [7] , [8] . However, during cultivation, collection, manufacture, and processing, ganoderma lucidum spore powder is vulnerable to plasticizer contamination, posing a major risk to public health [9] , [10] .…”

Section: Introductionmentioning

confidence: 99%

Ultrasonic-assisted supercritical fluid separation removing plasticizers from ganoderma lucidum spores’ oil

Li,

Ma,

Shen

et al. 2023

Ultrasonics Sonochemistry

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Bioactivities and industrial standardization status of Ganoderma lucidum: A comprehensive review

Wu,

Zhang,

Yin

et al. 2024

Heliyon

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Lanostane triterpenoids from Ganoderma lucidum and their inhibitory effects against FAAH

Cited by 6 publications

References 38 publications

Effect of dissolved oxygen regulation on the content of ganoderic acid S and R in mycelium of Ganoderma lucidum in a two-stage culture by oscillatory-stationary culture

Effect of dissolved oxygen regulation on the content of ganoderic acid S and R in mycelium of Ganoderma lucidum in a two-stage culture by oscillatory-stationary culture

Ultrasonic-assisted supercritical fluid separation removing plasticizers from ganoderma lucidum spores’ oil

Bioactivities and industrial standardization status of Ganoderma lucidum: A comprehensive review

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