“…However, of these 43 publications 36 had to be excluded, because they either lacked specific data on severe acute cholecystitis [12,[23][24][25][26][27][28][29], included forms other than gangrenous or empyematous cholecystitis [30,31], failed to describe patient selection [32][33][34][35], reported on fewer than 10 patients [14,[36][37][38][39], contained no comparison on severe acute cholecystitis versus nonsevere acute cholecystitis [40][41][42][43][44][45][46] or results not referred to histological findings [13,[15][16][17][47][48][49][50]. One study was a double publication [11].…”