Abstract:Minimal invasive mapping and excision of SLN of the rectum using a RI is feasible. The sensitivity for detecting SLN was high (93%). The application of this procedure on humans seems to be possible.
“…Although the technique has been studied widely in colorectal cancer as an adjunct to upstage tumours undergoing radical surgery, no clinical study has yet investigated the technique in a preoperative setting. Only one study has assessed SLNM as a preoperative staging modality in a porcine model86. A mixture of 99m Tc and patent blue V dye was administered endoscopically into the rectum of 30 pigs.…”
Section: Can Nodal Staging Be Enhanced For Rectal Conservation?mentioning
Rectal tumours showing an excellent response to CRT may be suitable for local excision, with equivalent outcomes to radical surgery. This approach should be the subject of prospective clinical trials in specialist centres.
“…Although the technique has been studied widely in colorectal cancer as an adjunct to upstage tumours undergoing radical surgery, no clinical study has yet investigated the technique in a preoperative setting. Only one study has assessed SLNM as a preoperative staging modality in a porcine model86. A mixture of 99m Tc and patent blue V dye was administered endoscopically into the rectum of 30 pigs.…”
Section: Can Nodal Staging Be Enhanced For Rectal Conservation?mentioning
Rectal tumours showing an excellent response to CRT may be suitable for local excision, with equivalent outcomes to radical surgery. This approach should be the subject of prospective clinical trials in specialist centres.
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