Laparoscopic Splenectomy for Massive Splenomegaly Accompanied by Malignant Lymphoma: A Two-Case Report

Abstract

Currently, there are no clear indications for laparoscopic splenectomy for cases involving splenomegaly accompanied by malignant disease. Here, we report the safe and successful execution of laparoscopic splenectomy in two patients with massive splenomegaly. Two male patients were in their 40 s and 70 s. Computed tomography revealed the long diameters of their spleens to be 24 and 21 cm, and the operation times were 324 and 271 min. Intraoperative blood loss were 10 and 56 cc. Both spleens weighed approximately 1,500 g. Pathological diagnoses were splenic marginal zone lymphoma and mantle cell lymphoma. Manipulation of the splenic hilum was a safe and effective approach for laparoscopic splenectomy in the two patients with massive splenomegaly (diameter ＞ 20 cm).