Laparoscopic ventral hernia repair using a novel intraperitoneal lightweight mesh coated with hyaluronic acid: 1-year follow-up from a case–control study using the Hernia-Club registry

Gillion, J.-F.; Fromont, G.; Lepère, M.; Letoux, Nathalie; Dabrowski, André; Zaranis, C.; Barrat, Christophe

doi:10.1007/s10029-016-1501-y

Cited by 15 publications

(3 citation statements)

References 31 publications

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“…The German Herniamed Registry included both inguinal and ventral hernias and was launched in 2009 [9]. In France the Club Hernie (CH) started their ventral hernia registry in 2011 across 30 specialized hernia surgeons [10]. Two registries were launched in 2012: EuraHS [8], and the Spanish Registro Español de Eventraciones (EVEREG) [11].…”

Section: Resultsmentioning

confidence: 99%

Comparison of hernia registries: the CORE project

Kyle-Leinhase

Köckerling

Jørgensen

et al. 2018

Hernia

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IntroductionThe aim of the international CORE project was to explore the databases of the existing hernia registries and compare them in content and outcome variables.MethodsThe CORE project was initiated with representatives from all established hernia registries (Danish Hernia Database, Swedish Hernia Registry, Herniamed, EuraHS, Club Hernie, EVEREG, AHSQC) in March 2015 in Berlin. The following categories were used to compare the registries: initiation and funding, data collection and use for certification of hernia centers, patient data and data protection, operative data, registration of complications and follow-up data.ResultsThe Danish Hernia Database is the only one to qualify as a genuine national registry where participation is compulsory for entry of all procedures by all surgeons performing a hernia operation. All other registries have to be considered as voluntary and completeness of data depends upon the participating hospitals and surgeons. Only the Danish Hernia Database and the Swedish Hernia Registry are publicly funded. All other registries are reliant on financial support from the medical technology industry. As an incentive for voluntary participation in a hernia registry, hospitals or surgeons are issued a certificate confirming that they are taking part in a quality assurance study for hernia surgery. Due to data protection and privacy regulations, most registries are obliged or have chosen to enter their patient data anonymously or coded. The Danish Hernia Database and Swedish Hernia Registry utilize a national personal patient code. In the Herniamed Registry, patient data are saved in a coded and anonymous format after obtaining the patient’s informed consent.ConclusionDespite the differences in the way data are collected for each of the listed hernia registries, the data are indispensable in clinical research.

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Section: Resultsmentioning

confidence: 99%

Comparison of hernia registries: the CORE project

Kyle-Leinhase

Köckerling

Jørgensen

et al. 2018

Hernia

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“…Although the long-term rate of recurrence has remarkedly decreased by using meshes, problematic issues remain, including repair failure, dysfunctional healing, and mesh-related complications . Therefore, currently, efforts are being made to design and modify the mesh to reinforce the abdominal wall and retain its characteristic shape and physical functions. − …”

Section: Introductionmentioning

confidence: 99%

Functionalized Strategies and Mechanisms of the Emerging Mesh for Abdominal Wall Repair and Regeneration

Liu

Wei

2021

ACS Biomater. Sci. Eng.

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Meshes have been the overwhelmingly popular choice for the repair of abdominal wall defects to retrieve the bodily integrity of musculofascial layer. Broadly, they are classified into synthetic, biological and composite mesh based on their mechanical and biocompatible features. With the development of anatomical repair techniques and the increasing requirements of constructive remodeling, however, none of these options satisfactorily manages the conditional repair. In both preclinical and clinical studies, materials/agents equipped with distinct functions have been characterized and applied to improve meshaided repair, with the importance of mesh functionalization being highlighted. However, limited information exists on systemic comparisons of the underlying mechanisms with respect to functionalized strategies, which are fundamental throughout repair and regeneration. Herein, we address this topic and summarize the current literature by subdividing common functions of the mesh into biomechanics-matched, macrophage-mediated, integrationenhanced, anti-infective and antiadhesive characteristics for a comprehensive overview. In particular, we elaborate their effects separately with respect to host response and integration and discuss their respective advances, challenges and future directions toward a clinical alternative. From the vastly different approaches, we provide insight into the mechanisms involved and offer suggestions for personalized modifications of these emerging meshes.

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“…Prostheses have represented a successful method of ventral hernia repair in clinical practice. , However, using unmodified prostheses directly for abdominal wall repair still represents a formidable challenge. For instance, polypropylene (PP) is one of the most commonly used prosthetic materials for repairing abdominal wall defects, but possibly serious abdominal adhesions can occur after mesh implantation, as well as some consequent complications, such as chronic pain, intestinal obstruction, and fistula.…”

Section: Introductionmentioning

confidence: 99%

Combination of Polypropylene Mesh and in Situ Injectable Mussel-Inspired Hydrogel in Laparoscopic Hernia Repair for Preventing Post-Surgical Adhesions in the Piglet Model

Zhang

Long

et al. 2020

ACS Biomater. Sci. Eng.

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Polypropylene (PP) mesh has been used successfully for a long time in clinical practice as an impressive prosthesis for ventral hernia repair. To utilize a physical barrier for separating mesh from viscera is a general approach for preventing adhesions in clinical practice. However, a serious abdominal adhesion between the mesh and viscera can possibly occur post-hernia, especially with the small intestine; this can lead to a series of complications, such as chronic pain, intestinal obstruction, and fistula. Thus, determining how to prevent abdominal adhesions between the mesh and viscera is still an urgent clinical problem. In this study, a dopamine-functionalized polysaccharide derivative (oxidized-carboxymethylcellulose-g-dopamine, OCMC-DA) was synthesized; this was blended with carboxymethylchitosan (CMCS) to form a hydrogel (OCMC-DA/CMCS) in situ at the appropriate time. The physical and chemical properties of the hydrogel were characterized successfully, and its excellent biocompatibility was presented by the in vitro cell test. The combination of this hydrogel and PP mesh was used in laparoscopic surgery for repairing the abdominal wall defect, where the hydrogel could become fixed in situ on the PP mesh to form an anti-adhesion gel-mesh. The results showed that the gel-mesh could prevent abdominal adhesions effectively in the piglet model. Moreover, the histology and immunohistochemical staining proved that the gel-mesh could effectively alleviate the inflammation reaction and deposition of collagen around the mesh, and it did not disturb the integration between mesh and abdominal wall. Thus, the gel-mesh has superior tissue compatibility.

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Laparoscopic ventral hernia repair using a novel intraperitoneal lightweight mesh coated with hyaluronic acid: 1-year follow-up from a case–control study using the Hernia-Club registry

Abstract: Ventralight ST™ mesh is effective and well tolerated in LVHR, producing very low complication and recurrence rates in the short and medium term. The results are comparable to those achieved with other types of mesh.

Cited by 15 publications

References 31 publications

Comparison of hernia registries: the CORE project

Comparison of hernia registries: the CORE project

Functionalized Strategies and Mechanisms of the Emerging Mesh for Abdominal Wall Repair and Regeneration

Combination of Polypropylene Mesh and in Situ Injectable Mussel-Inspired Hydrogel in Laparoscopic Hernia Repair for Preventing Post-Surgical Adhesions in the Piglet Model

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