Heat transfer capabilities of the heat exchangers require enhancements to save energy and decrease their size. For this purpose, the swirl generators have been widely preferred. However, the swirler inserts have not reached their optimum shape. Thus, this study experimentally and numerically investigates the impact of novel 3D-printed swirler inserts with varying twist angles in the range of 0°–450° on the thermo-hydraulic performance of solar absorber tube heat exchangers under laminar flow (Re = 513–2054) condition. Friction factor, Nusselt number, and performance evaluation criterion (PEC) were used to assess heat exchanger performance, and related correlations are provided. Tangential velocity components were also used to explore fluid flow characteristics in local analysis. Numerical investigation was done by using computational fluid dynamics adopting Finite Volume Method in ANSYS Fluent. Results show that 3D-printed swirlers considerably increase heat transfer compared to plain tube. The swirler with a twist angle of 450° led to the maximum enhancements of nearly 217% in average Nusselt number and around 1630% in friction factor at Reynolds number of 2054. Overall, increasing Reynolds number enhanced Nusselt number. The highest PEC of 1.15 was observed at a Reynolds number of 1031 using the swirler with 150° twist angle. Flow near the swirler has higher tangential velocities, hence contributing to local Nusselt number enhancement up to 453.8% compared to plain tube when swirler with twist angle of 450° utilized. It is anticipated that findings of this study can guide further related research and increase the usage of swirlers in heat exchangers.