Large granular leukemia with concurrent central nervous system and articular infiltration in a cat

Bouzouraa, T.; Rannou, Benoît; Sayag, D.; Ponce, Frédérique; Ségard, E.; Belluco, Sara; Cadoré, Jean‐Luc; Chabanne, Luc

doi:10.1016/j.anicom.2018.06.002

Cited by 2 publications

(3 citation statements)

References 27 publications

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“…It most commonly occurs as intestinal lymphoma in cats, rarely with CNS involvement 6 . Brain involvement has been reported in one feline case 7 . Ocular LGL lymphoma has been described in one caracal 8 .…”

Section: Discussionmentioning

confidence: 99%

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Diagnosis of lymphoma based on magnetic resonance imaging, analysis of cerebrospinal fluid, intraocular fluid and fine‐needle aspirate of a uveal mass lesion in a dog

Santifort,

Plonek,

Kraijer‐Huver

et al. 2024

Vet Record Case Reports

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A 10.5‐year‐old, male, entire labrador retriever dog was presented for chronic progressive ataxia and recent onset of a left‐sided head tilt and salivation. Neurological examination findings were deemed consistent with a multifocal brain and spinal cord neuroanatomic localisation. Ophthalmological examination of the right eye revealed pupil shape abnormality (dyscoria), a pale uveal mass lesion and white cellular sediment in the anterior chamber. Magnetic resonance imaging of the brain, eyes, thoracolumbar and lumbosacral spinal cord and surrounding structures showed multiple lesions affecting the central nervous system (brain), peripheral nervous system (left trigeminal nerve) and right eye. Cerebrospinal fluid, right eye anterior chamber fluid and fine‐needle aspirate biopsy of the uveal mass lesion yielded a cytological diagnosis of lymphoma (suspected large granular lymphocytic). The dog was discharged with palliative treatment and euthanased at home 4 days later. This case report documents the cytological diagnosis of lymphoma in the cerebrospinal fluid, intraocular fluid and fine‐needle aspirate of a uveal mass in a dog.

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Section: Discussionmentioning

confidence: 99%

“…6 Brain involvement has been reported in one feline case. 7 Ocular LGL lymphoma has been described in one caracal. 8 Spinal cord LGL lymphoma has been reported in a dog.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of lymphoma based on magnetic resonance imaging, analysis of cerebrospinal fluid, intraocular fluid and fine‐needle aspirate of a uveal mass lesion in a dog

Santifort,

Plonek,

Kraijer‐Huver

et al. 2024

Vet Record Case Reports

View full text Add to dashboard Cite

show abstract

“…O tratamento é estabelecido de acordo com o quadro clínico e suas manifestações, tendo como objetivo destruir as células neoplásicas. Os protocolos utilizados para o tratamento de linfomas são os mesmos realizados em animais com LLA e LLC (CAMPBELL et al, 2012;BOUZOURAA et al, 2018). O uso de quimioterápicos é limitado em casos de anemia, trombocitopenia e neutropenia.…”

Section: Introductionunclassified

Leucemia linfoide aguda em gatos infectados pelo vírus da leucemia felina com diagnóstico presuntivo de 12 casos

Paixão¹,

Paixão

Silvestre³

et al. 2021

CONJ

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A leucemia é definida como uma neoplasia de células hematopoiéticas. Pode ser classificada em quadros agudos ou crônicos, sendo o vírus da FeLV intimamente ligado a causa de leucemias agudas. Em caráter retrospectivo, nove animais diagnosticados FeLV positivos, com a evidenciação de bicitopenia, associada ao predomínio de linfócitos (superior a 80%) foram selecionados para uma análise hematológica. Todos os animais apresentaram linfocitose acentuada (> 13.000 céls/μL) e em apenas dois gatos foram encontrados linfoblastos. O protocolo quimioterápico Wisconsin-Madison modificado foi realizado em quatro gatos, mas somente o gato 7 sobreviveu e obteve melhora do quadro clínico. Os nove gatos avaliados neste trabalho apresentaram características compatíveis com um quadro leucêmico agudo, tendo uma sobrevida de 16 dias, o que indica ser uma enfermidade de curso rápido e prognóstico ruim, dificultando a realização de exames mais complexos para um diagnóstico definitivo.

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Large granular leukemia with concurrent central nervous system and articular infiltration in a cat

Cited by 2 publications

References 27 publications

Diagnosis of lymphoma based on magnetic resonance imaging, analysis of cerebrospinal fluid, intraocular fluid and fine‐needle aspirate of a uveal mass lesion in a dog

Diagnosis of lymphoma based on magnetic resonance imaging, analysis of cerebrospinal fluid, intraocular fluid and fine‐needle aspirate of a uveal mass lesion in a dog

Leucemia linfoide aguda em gatos infectados pelo vírus da leucemia felina com diagnóstico presuntivo de 12 casos

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