Thanks to the advantage of balancing nonlinear effects and transverse mode instability, vary core diameter active fiber (VCAF) has been widely used in high power ytterbium-doped fiber lasers in recent years. Up to now, VCAF has developed from the basic form of the original tapered fiber to the spindle-shaped and saddle-shaped fiber with different characteristics and has been applied in conventional fiber lasers, oscillating–amplifying integrated fiber lasers, and quasi-continuous wave fiber lasers and successfully improved the performance of these lasers. In the present study, a 6110 W fiber laser amplifier is realized based on a tapered fiber. The maximum output power of a fiber laser amplifier based on spindle-shaped fibers is 6020 W with a beam quality of M2~1.86. In this paper, we first introduce the basic concept of VCAF and summarize its main fabrication methods and advantages in high-power fiber laser applications. Then, we will present the recent research results of high-power fiber laser employing VCAF in our group and clarify the outstanding advantages of VCAF compared with the constant core diameter active fiber (CCAF).