Large Pelvic Mass in a Female Adolescent: Atypical Presentation and Successful Treatment of Extraskeletal Ewing Sarcoma

Abstract

Extraskeletal Ewing sarcoma is a rare soft tissue tumor primarily affecting pediatric patients. The treatment is currently based on a multidisciplinary approach which allows, in cases of localized disease, good survival rates. We report the case of a 15-year-old female patient with a rapidly growing suspected pelvic mass misdiagnosed following the preliminary radiological exams, which assessed the findings as a mass of ovarian origin. The girl underwent surgery and, thanks to histopathological, immunohistochemical and real-time polymerase chain reaction (RT-PCR) examinations, it was possible to make the right diagnosis and to administer the best treatment in terms of surgery, chemotherapy and radiotherapy, obtaining a long disease-free interval and no recurrence to date.

Editorial: Update in pediatric gynecology

“…There are many challenges in implementing pediatric oncology treatment pathways, for example, the need to evaluate accurately the timing of the various types of medical and surgical treatment (surgery, radiotherapy, chemotherapy, preservation of reproductive capacity) and the need to contextualize the epidemiology of female tumors arising at a young age, the diagnostic suspicion and consequently the appropriate diagnostic imaging process and endoscopic procedures ( 5 ).…”