Large volume injection in ion chromatography

García-Ruiz, Silvia; Moldován, Mariella; Alonso, J. Ignacio García

doi:10.1016/j.chroma.2007.03.048

Cited by 17 publications

(12 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unfortunately, no separation of strontium from other matrix elements (such as calcium) could be accomplished and this could affect measurements using MC-ICP-MS instruments. The chromatographic procedure used here 25 separates strontium from other alkaline and alkaline earth elements which eluted in the dead volume. Additionally, carbon containing compounds in cider, detected as 13 C in the quadrupole instrument, eluted well before the strontium peak.…”

Section: Resultsmentioning

confidence: 99%

“…The optimisation of the ion chromatographic separation using large volume injection is described in detail elsewhere. 25 In brief, Rb and Sr were chromatographically separated using 900 mM nitric acid and 5 mM 18-crown-6 ether eluent using 3 mL volume sample injection. Flat-topped chromatographic peaks, with about 3 minutes of stable plateau for on-line data acquisition at both Rb and Sr peaks, were obtained when the composition of the mobile phase was identical to the sample solution.…”

Section: Chromatographic Separationmentioning

confidence: 99%

“…24 Hence, it would be advisable to develop chromatographic procedures which showed no isotopic fractionation effects and eliminate the need for fast response in the Faraday cup amplifiers. Recent work in our laboratory 25 on the on-line separation of Rb and Sr using ion chromatography showed that flat-topped chromatographic peaks of several minutes could be obtained using large volume injection (3 mL) and a mobile phase containing 900 mM nitric acid in the presence of 5 mM 18-crown-6 ether. The chromatographic method was optimised using a quadrupole ICP-MS instrument and showed that Rb and other matrix elements (such as Ca, Mg, K and Na) eluted at the dead volume, while Sr was strongly retained and eluted as a flat-topped chromatographic peak.…”

Section: Introductionmentioning

confidence: 99%

“…The chromatographic method was optimised using a quadrupole ICP-MS instrument and showed that Rb and other matrix elements (such as Ca, Mg, K and Na) eluted at the dead volume, while Sr was strongly retained and eluted as a flat-topped chromatographic peak. From the developed chromatographic method, 25 it was clear that isotope fractionation effects would be absent and no fast response amplifiers would be required at the flat top of the peak.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Measurement of strontium isotope ratios by MC-ICP-MS after on-line Rb–Sr ion chromatography separation

García-Ruiz

Moldován

Alonso

2008

J. Anal. At. Spectrom.

Self Cite

View full text Add to dashboard Cite

Large volume injection ion chromatography has been evaluated for the precise and accurate measurement of strontium isotope ratios by multicollector ICP-MS. On-line coupling of the ion chromatograph to the MC-ICP-MS instrument allowed the complete separation of isobaric rubidium and other matrix elements (Ca, Mg, Na and K) and the measurement of strontium isotope ratios on flat-topped chromatographic peaks of ca. 3 minutes duration. No drift in the strontium isotope ratios was observed during strontium elution and mass bias could be corrected using either the 86 Sr/ 88 Sr isotope ratio (internal correction) or the observed 87 Rb/ 85 Rb isotope ratio (external correction) in the real samples. Typical internal precisions obtained with the selected measurement and correction conditions were about 2 times lower than the precisions obtained with continuous sample introduction for a solution 50 ng g À1 of Sr NIST SRM 987 in HNO 3 2% (typical standard deviations of 0.00022-0.00036 for the corrected 87 Sr/ 86 Sr ratio in comparison to 0.00014-0.00020 for continuous sample introduction). The method was applied to the measurement of strontium isotope ratios in cider samples and the results agreed with previous data obtained after an off-line Rb-Sr separation procedure using the Sr-Spec chelating material. The precision obtained for the real samples was poorer than previous data due to the low concentration of strontium in the measured samples. The method was also applied to other sample types (soil leachates, apple leaves and apples) to study the transference of strontium isotope ratios in the soil-tree-cider system.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Chromatographic Separationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Measurement of strontium isotope ratios by MC-ICP-MS after on-line Rb–Sr ion chromatography separation

García-Ruiz

Moldován

Alonso

2008

J. Anal. At. Spectrom.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Besides these manual separation techniques, also automated chromatographic procedures have been developed [24][25][26][27] and even coupled on-line to (MC-)ICP-MS for subsequent Sr isotope ratio analysis, 13,28,29 although quantitative Sr recoveries were not in all cases obtained.…”

Section: -23mentioning

confidence: 99%

Systematic evaluation of a strontium-specific extraction chromatographic resin for obtaining a purified Sr fraction with quantitative recovery from complex and Ca-rich matrices

Muynck

Huelga-Suarez

Heghe

et al. 2009

J. Anal. At. Spectrom.

111

View full text Add to dashboard Cite

This paper presents a systematic evaluation of a commercially available strontium-specific extraction chromatographic resin based on a crown ether (Sr specÔ), for use in applications of Sr isotope ratio analysis dealing with samples displaying a complex and/or Ca-rich matrix composition. A protocol, consisting of (i) loading a sample digest in 7 M HNO 3 onto the resin, (ii) rinsing the resin with 7 M HNO 3 to remove concomitant matrix elements and (iii) rinsing the resin with 0.05 M HNO 3 to strip off the purified Sr fraction, was found to provide the best results. The performance in terms of (i) the purity of the Sr fraction obtained, (ii) the efficiency of Rb/Sr and Ca/Sr separation, (iii) the Sr recovery from samples with a complex and Ca-rich matrix composition and (iv) the Sr isotope ratios obtained using multi-collector ICP-MS, was evaluated for various amounts (250, 500, 750 and 2000 mL) of resin using digests of bone and soil certified reference materials, dental tissues, fluorite and glass samples. Further, it was investigated whether or not the isolation protocol introduces Sr isotopic fractionation. Also the possibility of regenerating the resin after use, allowing multiple use of the resin, was assessed. Finally, the Sr isotopic composition of 2 bone (NIST SRM 1400 Bone Ash and NIST SRM 1486 Bone Meal) and 2 soil (BCR CRM 141 Calcareous Loam Soil and BCR CRM 142 Light Sandy Soil) certified reference materials was determined. The method was shown to be fit-for-purpose for population migration studies and provenancing of archaeological artefacts, and is expected to be suited for a broad range of Sr isotope ratio applications.

show abstract