Laser in situ keratomileusis application for myopia over minus 14 diopter with long-term follow-up

Oruçoğlu, Faik; Kingham, James D.; Kendüşim, Mahir; Ayoğlu, Buket; Toksu, Berrin; Göker, Sinan

doi:10.1007/s10792-012-9595-4

Cited by 16 publications

(17 citation statements)

References 31 publications

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“…Rosman et al stated that mean regression at 10 years after LASIK was −1.86 D in eyes with myopia of −14.33 ± 2.11 D [17]. Oruçoğlu et al and Lim et al described that mean final refraction was −6.09 D and −1.09 D in eyes with myopia of −21.70 ± 5.86 D and −5.73 ± 2.76 D, respectively [18, 20]. In the current study, similarly, we found refractive regression of −0.74 ± 0.99 D from 3 months to 12 years postoperatively.…”

Section: Discussionmentioning

confidence: 99%

Twelve-Year Follow-Up of Laser In Situ Keratomileusis for Moderate to High Myopia

Ikeda

Shimizu

Igarashi

et al. 2017

BioMed Research International

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Purpose To assess the long-term clinical outcomes of conventional laser in situ keratomileusis (LASIK) for moderate to high myopia. Methods We retrospectively examined sixty-eight eyes of 37 consecutive patients who underwent conventional LASIK for the correction of myopia (−3.00 to −12.75 diopters (D)). At 3 months and 1, 4, 8, and 12 years postoperatively, we assessed the safety, efficacy, predictability, stability, mean keratometry, central corneal thickness, and adverse events. Results The safety and efficacy indices were 0.82 ± 0.29 and 0.67 ± 0.37, respectively, 12 years postoperatively. At 12 years, 53% and 75% of the eyes were within 0.5 and 1.0 D, respectively, of the targeted correction. Manifest refraction changes of −0.74 ± 0.99 D occurred from 3 months to 12 years after LASIK (p < 0.001). We found a significant correlation of refractive regression with the changes in keratometric readings from 3 months to 12 years postoperatively (Pearson correlation coefficient, r = −0.28, p = 0.02), but not with the changes in central corneal thickness (r = −0.08, p = 0.63). No vision-threatening complications occurred in any case. Conclusions Conventional LASIK offered good safety outcomes during the 12-year observation period. However, the efficacy and the predictability gradually decreased with time owing to myopic regression in relation to corneal steepening.

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Section: Discussionmentioning

confidence: 99%

Twelve-Year Follow-Up of Laser In Situ Keratomileusis for Moderate to High Myopia

Ikeda

Shimizu

Igarashi

et al. 2017

BioMed Research International

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“…There was a significant average trend towards myopic regression of − 0.51 D between 1 and 24 months (P < 0.001), which is small considering this VHM group. Patients with high myopia are more likely to regress, with regression being reported to be more pronounced between 3 and 12 months [15,[33][34][35]. There may be less regression here than expected due to newer aspheric larger ablation profiles (Custom-Q®), improving stability.…”

Section: Complicationsmentioning

confidence: 99%

Refractive, visual, and subjective quality of vision outcomes for very high myopia LASIK from − 10.00 to − 13.50 diopters

Kam

Gauvin

Adiguzel³

et al. 2020

BMC Ophthalmol

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Background: To evaluate laser-assisted in situ keratomileusis (LASIK) outcomes, subjective quality of vision (QoV) and patient satisfaction in eyes with very high myopia (VHM) above − 10.00 diopters (D). Methods: Consecutive myopic and myopic-astigmatism eyes with spherical equivalent (SEQ) ranging between − 10.00 to − 13.50 D underwent LASIK with the WaveLight® Allegretto Wave® Eye-Q 400 Hz excimer laser. Treatment accuracy, efficacy, safety, stability, cylinder vectors, and higher-order aberrations were evaluated, together with subjective QoV and night vision disturbances (NVDs). Results: 114 eyes had a preoperative SEQ of − 11.02 ± 0.81 D, with a median follow-up of 24 months. A total of 72, 84, and 94% of eyes were within ± 0.50, ± 0.75 and ± 1.00 D of intended SEQ (R 2 = 0.71). The efficacy index was 0.93 ± 0.20, with 51 and 81% of eyes achieving 20/20 and 20/25. The astigmatism correction index was 0.95 ± 0.33. The safety index was 1.05 ± 0.12. The average myopic regression was − 0.51 ± 0.38 D. Preoperative QoV scores improved significantly postoperatively (7.5 ± 0.8 vs. 9.1 ± 0.7; P < 0.001), with less NVDs (P < 0.001). Total, spherical and coma root mean square (RMS) postoperative ocular higher-order aberrations were 1.07 ± 0.34, 0.67 ± 0.25, and 0.70 ± 0.40 μm. Conclusions: Very high myopia LASIK between − 10.00 to − 13.50 D is safe and results in good visual outcomes, with high patient satisfaction and a significant improvement in patient-reported QoV after surgery. Appropriately selected patients within this very high myopia group can be included as LASIK candidates.

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“… 3 Specifically, in correcting moderate to high myopia (equal or more than −6.00 D in the least-minus meridian), 4 , 5 there have been reports in the past indicating significant long-term regression. 6 – 8 The work by Alió et al 9 reported that 20.8% of high myopia cases required retreatment because of over- or undercorrection, or regression. Other studies have shown that the risk of regression may be between 5% and 27%.…”

Section: Introductionmentioning

confidence: 99%

Comparison of prophylactic higher fluence corneal cross-linking to control, in myopic LASIK, one year results

Kanellopoulos¹,

Asimellis²,

Karabatsas³

2014

OPTH

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PurposeTo compare 1-year results: safety, efficacy, refractive and keratometric stability, of femtosecond myopic laser-assisted in situ keratomileusis (LASIK) with and without concurrent prophylactic high-fluence cross-linking (CXL) (LASIK-CXL).MethodsWe studied a total of 155 consecutive eyes planned for LASIK myopic correction. Group A represented 73 eyes that were treated additionally with concurrent prophylactic high-fluence CXL; group B included 82 eyes subjected to the stand-alone LASIK procedure. The following parameters were evaluated preoperatively and up to 1-year postoperatively: manifest refractive spherical equivalent (MRSE), refractive astigmatism, visual acuity, corneal keratometry, and endothelial cell counts. We plotted keratometry measurements pre-operatively and its change in the early, interim and later post-operative time for the two groups, as a means of keratometric stability comparison.ResultsGroup A (LASIK-CXL) had an average postoperative MRSE of −0.23, −0.19, and −0.19 D for the 3-, 6-, and 12-month period, respectively, compared to −6.58±1.98 D preoperatively. Flat keratometry was 37.69, 37.66, and 37.67 D, compared to 43.94 D preoperatively, and steep keratometry was 38.35, 38.36, and 38.37 D, compared to 45.17 D preoperatively. The predictability of Manifest Refraction Spherical Equivalent (MRSE) correction showed a correlation coefficient of 0.979. Group B (stand-alone LASIK) had an average postoperative MRSE of −0.23, −0.20, and −0.27 D for the 3-, 6-, and 12-month period, respectively, compared with −5.14±2.34 D preoperatively. Flat keratometry was 37.65, 37.89, and 38.02 D, compared with 43.15 D preoperatively, and steep keratometry was 38.32, 38.57, and 38.66 D, compared with 44.07 D preoperatively. The predictability of MRSE correction showed a correlation coefficient of 0.970. The keratometric stability plots were stable for the LASIK CXL group and slightly regressing in the standard LASIK group, a novel stability evaluation metric that may escape routine acuity and refraction measurements.ConclusionApplication of prophylactic CXL concurrently with myopic LASIK surgery appears to contribute to improved refractive and keratometric stability compared to standard LASIK. The procedure appears safe and provides a new potential for LASIK correction.

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Laser in situ keratomileusis application for myopia over minus 14 diopter with long-term follow-up

Cited by 16 publications

References 31 publications

Twelve-Year Follow-Up of Laser In Situ Keratomileusis for Moderate to High Myopia

Twelve-Year Follow-Up of Laser In Situ Keratomileusis for Moderate to High Myopia

Refractive, visual, and subjective quality of vision outcomes for very high myopia LASIK from − 10.00 to − 13.50 diopters

Comparison of prophylactic higher fluence corneal cross-linking to control, in myopic LASIK, one year results

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Laser in situ keratomileusis application for myopia over minus 14 diopter with long-term follow-up

Cited by 16 publications

References 31 publications

Twelve-Year Follow-Up of Laser In Situ Keratomileusis for Moderate to High Myopia

Twelve-Year Follow-Up of Laser In Situ Keratomileusis for Moderate to High Myopia

Refractive, visual, and subjective quality of vision outcomes for very high myopia LASIK from − 10.00 to − 13.50 diopters

Comparison of prophylactic higher fluence corneal cross-linking to control, in myopic LASIK,&nbsp;one year results

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Comparison of prophylactic higher fluence corneal cross-linking to control, in myopic LASIK, one year results