Laser-induced breakdown spectroscopy: a tool for real-time, in vitro and in vivo identification of carious teeth

Samek, Ota; Telle, Helmut H.; Beddows, D. C. S.

doi:10.1186/1472-6831-1-1

Cited by 89 publications

(50 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Samek et al [285][286][287] reported on quantitative LIBS analysis to study the presence of trace minerals in teeth. In these papers, selections of teeth from different age groups were investigated.…”

Section: Medical and Biological Applicationsmentioning

confidence: 99%

Laser Induced Breakdown Spectroscopy

Pasquini¹,

Cortez²,

Silva³

et al. 2007

J. Braz. Chem. Soc.

342

195

View full text Add to dashboard Cite

Esta revisão descreve os aspectos fundamentais, a instrumentação, as aplicações e tendências futuras de uma técnica analítica que se encontra em seu estágio de consolidação e que está em vias de estabelecer o seu nicho entre as técnicas espectrofotométricas modernas. A técnica é denominada Espectroscopia de Emissão em Plasma Induzido por Laser (em inglês, Laser Induced Breakdown Spectroscopy, LIBS) e sua principal característica está no uso de pulsos de laser como fonte de energia para vaporizar a amostra e excitar a emissão de radiação eletromagnética, a partir de seus elementos e/ou fragmentos moleculares. A radiação emitida é analisada por meio de instrumentos ópticos de alta resolução e as suas intensidades são medidas, usualmente com detectores rápidos de estado sólido. Em conjunto, esses dispositivos permitem a geração e a medida de um espectro de emissão de faixa ampla do fenômeno induzido pelo pulso de laser. O espectro registrado contém informação qualitativa e quantitativa que pode ser correlacionada com a identidade da amostra ou empregada na determinação da quantidade de seus constituintes. Essa revisão é dividida em quatro partes. A primeira aborda aspectos históricos da técnica e os conceitos teóricos relevantes associados com LIBS; então, os aspectos práticos de diversas abordagens experimentais e instrumentais empregadas na implementação da técnica são revistos de forma crítica; as aplicações encontradas na literatura, incluindo aquelas que empregam quimiometria, são classificadas e exemplificadas por meio de trabalhos relevantes recentemente publicados. Finalmente, uma tentativa de estabelecer uma avaliação global e as perspectivas futuras para a técnica é apresentada.This review describes the fundamentals, instrumentation, applications and future trends of an analytical technique that is in its early stages of consolidation and is establishing its definitive niches among modern spectrometric techniques. The technique has been named Laser Induced Breakdown Spectroscopy (LIBS) and its main characteristic stands in the use of short laser pulses as the energy source to vaporize samples and excite the emission of electromagnetic radiation from its elements and/or molecular fragments. The emitted radiation is analyzed by high resolution optics and the intensities are recorded, usually by fast triggered solid state detectors. Together, these devices allow producing and registering a wide ranging emission spectrum of the short-lived phenomenon induced by the laser pulse. The spectrum contains qualitative and quantitative information which can be correlated with sample identity or can be used to determine the amount of its constituents. This review is divided in four parts. First, the relevant historical and theoretical concepts associated with LIBS are presented; then the main practical aspects of the several experimental and instrumental approaches employed for implementation of the technique are critically described; the applications related in the literature, including those making use of chemometri...

show abstract

Section: Medical and Biological Applicationsmentioning

confidence: 99%

Laser Induced Breakdown Spectroscopy

Pasquini¹,

Cortez²,

Silva³

et al. 2007

J. Braz. Chem. Soc.

342

195

View full text Add to dashboard Cite

show abstract

“…The LIBS technique has proven its own clinical significance for other in vivo applications such as in dental practice for the identification of teeth affected by caries (Samek et al, 2000(Samek et al, , 2001. Kumar et al (2004) have demonstrated LIBS experiments to explore the possibility of using LIBS for in vivo cancer detection.…”

Section: Wwwintechopencommentioning

confidence: 99%

A Review of Pathological Biomineral Analysis Techniques and Classification Schemes

Giannossi¹,

Summa²

2012

An Introduction to the Study of Mineralogy

View full text Add to dashboard Cite

“…The technique can be used to identify elements and determine their concentrations in solids, liquids and gases [14]. High spatial resolution and absolute quantification, down to concentration levels of a few parts-per-million, can be achieved with this technique [15]. Furthermore, LIBS can be used in the real time analysis of multiple elements under open air conditions while requiring very small samples [16].…”

Section: Introductionmentioning

confidence: 99%

“…Mainly the concentrations of the different elements vary from tissue to tissue. Therefore, intensity levels of LIBS spectra have been used to provide information about the concentration of the elements present in the biological sample [15]. These differences in concentration can be used to differentiate between tissue samples of similar elemental composition that do not have unique identifying elements.…”

Section: Introductionmentioning

confidence: 99%

Qualitative tissue differentiation by analysing the intensity ratios of atomic emission lines using laser induced breakdown spectroscopy (LIBS): prospects for a feedback mechanism for surgical laser systems

Kanawade

Mahari

Klämpfl

et al. 2013

Journal of Biophotonics

View full text Add to dashboard Cite

The research work presented in this paper focuses on qualitative tissue differentiation by monitoring the intensity ratios of atomic emissions using ‘Laser Induced Breakdown Spectroscopy’ (LIBS) on the plasma plume created during laser tissue ablation. The background of this study is to establish a real time feedback control mechanism for clinical laser surgery systems during the laser ablation process. Ex-vivo domestic pig tissue samples (muscle, fat, nerve and skin) were used in this experiment. Atomic emission intensity ratios were analyzed to find a characteristic spectral line for each tissue. The results showed characteristic elemental emission intensity ratios for the respective tissues. The spectral lines and intensity ratios of these specific elements varied among the different tissue types. The main goal of this study is to qualitatively and precisely identify different tissue types for tissue specific laser surgery. (© 2013 WILEY-VCH Verlag GmbH &Co. KGaA, Weinheim)

show abstract

Laser-induced breakdown spectroscopy: a tool for real-time, in vitro and in vivo identification of carious teeth

Cited by 89 publications

References 22 publications

Laser Induced Breakdown Spectroscopy

Laser Induced Breakdown Spectroscopy

A Review of Pathological Biomineral Analysis Techniques and Classification Schemes

Qualitative tissue differentiation by analysing the intensity ratios of atomic emission lines using laser induced breakdown spectroscopy (LIBS): prospects for a feedback mechanism for surgical laser systems

Contact Info

Product

Resources

About