“…In this regard, sandblasting, plasma spraying, and acid etching have become the three most common approaches used to alter the surface topography and increase the specific surface area of implants. But the main problem of those treatments is the contamination of the surface during the modification procedure 16,17 . On the other hand, Laser beam irradiation is a clean and reproducible process, where the implant surface does not interact with any other materials for its modification during the irradiation.…”