Laser surgery for soft tissue purulent diseases

Chegin, Vyacheslav Mikhailovich; Skobelkin, Oleg K.; Brekhov, Eugeny Ivanovich

doi:10.1002/lsm.1900040308

Cited by 22 publications

(12 citation statements)

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“…Present-day C 0 2 laser systems utilize a continuous wave form that does not result in explosive disruption of the tumor surface [6] and that enables the sealing of vascular and lymphatic channels. Further, these systems have been shown to destroy cells, cell nuclei, and bacteria in the beam path, leading to the "sterilization" of wounds and a reduction in the incidence of wound infections, even in highly contaminated cases [7]. Many investigators [8-101 have demonstrated enhanced tumor cure rates in animals treated with C 0 2 laser surgery when compared to animals treated by conventional means.…”

Section: Discussionmentioning

confidence: 99%

Reduction of local tumor recurrence by excision with the CO₂ laser

et al. 1986

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This study was undertaken to determine the effect of CO2 laser surgery on the incidence of local recurrence following tumor resection. Thirty female Fisher 344 rats were implanted with R3230AC mammary carcinoma. All tumors were completely excised 18-21 days post-implantation. In 15 animals, the resection was done with a scalpel. Fifteen animals underwent laser excision with the Sharplan 733 CO2 laser (TEMoo, 125 mm handpiece, 25W continuous wave). Primary tumor size was 17.6 +/- 1.4 mm in the scalpel group and 21.2 +/- 6.3 mm in the laser group. Tumor recurred in 14/15 (93.4%) of the scalpel group and 5/15 (33.3%) of the laser group (p less than 0.001). The site of recurrence was incisional in 13/15 (86.7%) of the scalpel group and 3/15 (20%) of the laser group (p less than 0.001). Axillary metastases occurred in 2/15 (13.3%) in each group. The disease-free interval was 26 days in the laser group and 12 days in the scalpel group. The CO2 laser is an effective surgical adjunct to reduce local tumor seeding and recurrence.

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Section: Discussionmentioning

confidence: 99%

Reduction of local tumor recurrence by excision with the CO₂ laser

et al. 1986

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“…Most of the literature relating to the use of laser in treating PSD has detailed the use of cutting lasers. The continuous‐wave CO 2 laser has been used to treat various purulent diseases of soft tissue, including PSD 17,18 . There are many advantages of using a CO 2 laser to treat PSD.…”

Section: Discussionmentioning

confidence: 99%

Pilonidal Sinus Disease Treated by Depilation Using an 800 nm Diode Laser and Review of the Literature

Benedetto

Lewis

2006

Dermatologic Surgery

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“…These systems have been shown to destroy cells and bacteria in the beam path, leading to the "sterilization" of wounds and a reduction in the incidence of wound infection [10,11]. Recent studies [12][13][14], however, demonstrate that viable bacterial and viral particles are liberated into the laser plume under certain conditions.…”

Section: Discussionmentioning

confidence: 99%

Comparison of local tumor recurrence following excision with the CO₂ laser, Nd:YAG laser, and argon beam coagulator

et al. 1988

Lasers Surg Med

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This study compares the incidence of local tumor recurrence following primary excision with the CO2 laser, Nd:YAG laser (contact), Argon Beam Coagulator, or electrocautery. One hundred eight Fisher 344 rats with R3230AC mammary tumors (1.6 +/- 0.04 [SD] cm diameter) were used. All animals were randomized into groups of similar tumor size. In groups C and CS, excision was performed with a Sharplan 1060 CO2 laser (TEMoo, 25 W, continuous wave [CW], 0.2-mm spot size). Wounds in group CS were "sterilized" (0.5-mm spot size, 25 W, CW) by gently heating the wound without causing blanching or charring. In group N, a 0.4-mm contact Laser Blade and a Cooper 8000 Nd:YAG laser at 20 W CW was used. In groups SA1 and SA2, tumors were excised with the scalpel, and hemostasis and wound "sterilization" were accomplished with the Bard System 6000 Argon Beam Coagulator (ABC) at 40 W and 4 liters/min argon gas flow in SA1 and 12 liters/min in SA2. In group E, excision was accomplished at 40 W blend mode, 10 W spray mode. In group EA, excision was accomplished at 60 W cutting current, and hemostasis was achieved with the ABC. The animals were examined for evidence of recurrence for 34 days postoperatively. Mortalities were excluded from analysis. The incidence of recurrence was 11/14 (79%) in C, 6/16 (38%) in CS, 10/14 (71%) in SA1, 6/13 (46%) in SA2, 6/15 (40%) in N, 7/10 (70%) in EA, and 3/15 (20%) in E. Group E is statistically different (P less than .01) from groups EA, C, and SA1. Group C was different (P less than .01) from groups E, CS, and N. These results demonstrate an inverse relationship between tumor recurrence and local thermal effects at the surgical site. The ABC did not increase tumor recurrence. Contact YAG surgery was similar to CO2 laser excision and "sterilization." An attempt to study the influence of gas flow and pressure on local tumor recurrence and metastases should be made.

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Laser surgery for soft tissue purulent diseases

Cited by 22 publications

References 0 publications

Reduction of local tumor recurrence by excision with the CO₂ laser

Reduction of local tumor recurrence by excision with the CO₂ laser

Pilonidal Sinus Disease Treated by Depilation Using an 800 nm Diode Laser and Review of the Literature

Comparison of local tumor recurrence following excision with the CO₂ laser, Nd:YAG laser, and argon beam coagulator

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Laser surgery for soft tissue purulent diseases

Cited by 22 publications

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Reduction of local tumor recurrence by excision with the CO2 laser

Reduction of local tumor recurrence by excision with the CO2 laser

Pilonidal Sinus Disease Treated by Depilation Using an 800 nm Diode Laser and Review of the Literature

Comparison of local tumor recurrence following excision with the CO2 laser, Nd:YAG laser, and argon beam coagulator

Contact Info

Product

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Reduction of local tumor recurrence by excision with the CO₂ laser

Reduction of local tumor recurrence by excision with the CO₂ laser

Comparison of local tumor recurrence following excision with the CO₂ laser, Nd:YAG laser, and argon beam coagulator