Laser trabeculoplasty for open-angle glaucoma and ocular hypertension

Rolim-de-Moura, Christiane; Paranhos, Augusto; Loutfi, Mohamed; Burton, David L.; Wormald, Richard; Evans, Jennifer R

doi:10.1002/14651858.cd003919.pub3

Cited by 8 publications

(9 citation statements)

References 145 publications

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“…Scanning laser ophthalmoscopy, Doppler OCT, and other modified OCTs can be combined to examine capillary morphology and sensitively detect blood flow in the retina in early glaucoma (Aumann et al, 2019 ; Burns et al, 2019 ). However, at present, the only effective way to delay glaucoma progression is to reduce IOP using eye drops, surgery, or laser procedures (Schehlein and Robin, 2019 ; Rolim-De-Moura et al, 2022 ). Prostaglandins are the most common medication used to lower IOP by accelerating aqueous drainage through the uveal sclera (Jansook and Loftsson, 2022 ).…”

Section: Discussionmentioning

confidence: 99%

“…Other drugs, such as α-adrenergic agonists, β-adrenergic blockers, and carbonic anhydrase inhibitors are second-line drugs that are ineffective in reducing IOP and have side effects (Lu et al, 2017 ; Nocentini and Supuran, 2019 ; Stoner et al, 2022 ). Surgical or laser procedures are recommended when medication cannot sufficiently lower IOP (Schehlein and Robin, 2019 ; Rolim-De-Moura et al, 2022 ). In recent years, advances in surgery, drug delivery, and gene therapy have led to a new field of glaucoma treatment (Wan et al, 2021 ; Tawfik et al, 2022 ).…”

Section: Discussionmentioning

confidence: 99%

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A bibliometric analysis of apoptosis in glaucoma

Zhang

Wang²,

Tan³

et al. 2023

Front. Neurosci.

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BackgroundGlaucoma is the first irreversible and second blindness disease, which is characterized by the death of retinal ganglion cells (RGCs) and degeneration of the optic nerve. Previous works have indicated that apoptosis is the main reason for RGC death in glaucoma. Although many studies have investigated the mechanism of apoptosis and different strategies targeting apoptosis to protect the RGCs and finally recover the impaired vision in the glaucoma. However, the global trend and hotspots of apoptosis in glaucoma have not been well illustrated and discussed.MethodsDocuments were extracted from the Web of Science Core Collection on November 2, 2022. We selected articles and reviews published in English from January 1, 1999 to November 1, 2022 to perform visual analysis and statistical analysis of countries, institutions, authors, references and keywords by VOSviewer 1.6.18 and CiteSpace 5.8.ResultsThe publications about apoptosis in glaucoma show an increasing trend over time. Besides, the authors, institutions in the US and China published the most numbers of articles with the highest citation, which may be leading the research in the field of apoptosis in glaucoma. Last, series of advanced research results, technology and treatment for glaucoma, such as the discovery of key regulatory mechanisms on RGC apoptosis are emerging and will provide precise strategies for the treatment of glaucoma.ConclusionThis research will broaden our comprehension about the role of apoptosis in the process of glaucoma, and provide guidelines for us in basic research and disease treatment in the further.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A bibliometric analysis of apoptosis in glaucoma

Zhang

Wang²,

Tan³

et al. 2023

Front. Neurosci.

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“…Some questions and comments, although representing important potential reviews and research questions, were out of scope for Cochrane Eyes and Vision Reviews, such as reviews of prevalence; reviews of the coverage and quality of services around the world or S4). In addition, some suggested review questions were already covered by reasonably up-to-date Cochrane Reviews or review updates in progress [23][24][25][26][27][28] or were useful pointers to important outcomes to be considered in reviews, in particular impact on social, economic, educational, and quality of life outcomes and cost-effectiveness of interventions (Box 1).…”

Section: Round 2 Was Open To Participants Who Registered An Interest ...mentioning

confidence: 99%

“…Some questions and comments, although representing important potential reviews and research questions, were out of scope for Eyes and Vision Reviews, such as reviews of prevalence; reviews of the coverage and quality of services around the world or review of specific aspects of a health system; and review questions on conditions covered by other Cochrane Review Groups (e.g., retinopathy of prematurity is covered by Cochrane Neonatal and interventions for the management of headache in idiopathic intracranial hypertension covered by Cochrane Pain, Palliative and Supportive Care) (Supporting Information: Table S4). In addition, some suggested review questions were already covered by reasonably up-to-date Cochrane Reviews or review updates in progress [23][24][25][26][27][28] or were useful pointers to important outcomes to be considered in reviews, in particular impact on social, economic, educational, and quality of life outcomes and cost-effectiveness of interventions (Box 1).…”

Section: Round 2 Was Open To Participants Who Registered An Interest ...mentioning

confidence: 99%

Identifying important questions for Cochrane systematic reviews in Eyes and Vision: Report of a priority setting exercise

Evans

Gordon

Azuara‐Blanco

et al. 2023

Cochrane Evidence Synthesis and Methods

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Introduction Systematic reviews are important to inform decision‐making for evidence‐based health care and patient choice. Deciding which reviews should be prioritized is a key issue for decision‐makers and researchers. Cochrane Eyes and Vision conducted a priority setting exercise for systematic reviews in eye health care. Methods We established a steering group including practitioners, patient organizations, and researchers. To identify potential systematic review questions, we searched global policy reports, research prioritization exercises, guidelines, systematic review databases, and the Cochrane Library (CENTRAL). We grouped questions into separate condition lists and conducted a two‐round online modified Delphi survey, including a ranking request. Participants in the survey were recruited through social media and the networks of the steering group. Results In Round 1, 343 people ranked one or more of the condition lists. Participants were eye care practitioners (69%), researchers (37%), patients or carers (24%), research providers/funders (5%), or noneye health care practitioners (4%) and from all World Health Organization regions. Two hundred twenty‐six people expressed interest in completing Round 2 and 160 of these (71%) completed the Round 2 survey. Reviews on cataract and refractive error, reviews relevant to children, and reviews on rehabilitation were considered to have an important impact on the magnitude of disease and equity. Narrative comments emphasized the need for reviews on access to eye health care, particularly for underserved groups, including people with intellectual disabilities. Conclusion A global group of stakeholders prioritized questions on the effective and equitable delivery of services for eye health care. When considering the impact of systematic reviews in terms of reducing the burden of eye conditions, equity is clearly an important criterion to consider in priority‐setting exercises.

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“…The abovementioned reasons led to the re-evaluation of selective laser trabeculoplasty (SLT), which always had the potential but was not widely adopted as a therapeutic choice in glaucoma management due to the lack of robust evidence. [ 13 14 ] This approach has changed dramatically after the landmark Laser in Glaucoma and Ocular Hypertension Trial (LIGHT). [ 15 ] The LIGHT trial filled in this lacuna and provided 6-year follow-up data, allowing for a prominent shift in glaucoma practice patterns.…”

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confidence: 99%

Selective laser trabeculoplasty: An updated narrative review

Narayanaswamy,

Sood,

Thakur

2024

Indian Journal of Ophthalmology

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Selective laser trabeculoplasty (SLT) has experienced a resurgence in interest, primarily driven by promising findings from the Laser in Glaucoma and Ocular Hypertension Trial. By offering SLT as an initial drug-free treatment option, we may be able to thwart issues such as adherence and persistence that plague our current medical management protocols. In this comprehensive narrative review, we delve into the current body of literature that explores the utility of SLT across a wide spectrum of scenarios and glaucoma subtypes. We present evidence that provides valuable insight into the efficacy and benefits of SLT, positioning it as a viable option in the management of glaucoma. Careful consideration of the associated risks and challenges is also necessary for successful adoption into clinical practice. Despite the ample evidence supporting SLT’s efficacy, some questions remain regarding its long-term effects and the potential need for retreatment. This review aims to shed light on these aspects to guide clinicians in making informed decisions and tailoring treatment plans to individual patient needs. This review also provides the readers with a bird’s eye view of the potential impact of SLT and adds clarity to the various therapeutic protocols that one can follow to ensure optimal clinical outcomes for our patients.

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Laser trabeculoplasty for open-angle glaucoma and ocular hypertension

Abstract: Laser trabeculoplasty for open-angle glaucoma and ocular hypertension.

Cited by 8 publications

References 145 publications

A bibliometric analysis of apoptosis in glaucoma

A bibliometric analysis of apoptosis in glaucoma

Identifying important questions for Cochrane systematic reviews in Eyes and Vision: Report of a priority setting exercise

Selective laser trabeculoplasty: An updated narrative review

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