LASIK and the Ocular Surface

Toda, Ikuko

doi:10.1097/ico.0b013e31817f42c0

Cited by 74 publications

(60 citation statements)

References 32 publications

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“…The levels of topical lubricant use in our study are comparable with the incidence of dry-eye disease reported in other studies. 2,5,6 For example, in another study, 5 dry-eye disease after LASIK affected approximately 50% of patients at 1 week, 40% at 1 month, and 20% to 40% at 6 months.…”

Section: Discussionmentioning

confidence: 96%

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Comparison of dry-eye disease severity after laser in situ keratomileusis and laser-assisted subepithelial keratectomy

Dooley

Darcy

O’Keefe

2012

Journal of Cataract and Refractive Surgery

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Section: Discussionmentioning

confidence: 96%

“…5 Laser-assisted subepithelial keratectomy (LASEK) is also associated with transient postoperative dry-eye symptoms. 2,6 Lemp et al 7 report tear osmolarity as a new reliable metric for diagnosis and classification of dry-eye disease.…”

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confidence: 99%

Comparison of dry-eye disease severity after laser in situ keratomileusis and laser-assisted subepithelial keratectomy

Dooley

Darcy

O’Keefe

2012

Journal of Cataract and Refractive Surgery

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“…However, exploratory analyses suggested that dry eye symptoms were associated with visual Dry eye is one of the most common complications reported after LASIK surgery. 7,9,11,[35][36][37][38] Using the OSDI, with its limitations, 39 our findings for dry eye symptoms were incon- All correlations were performed using Spearman rank-order correlation coefficients (satisfaction score vs OSDI Score; all P < .001). Each panel shows analyses with satisfaction scores for 1 of 2 types of satisfaction: satisfaction with vision (A) and satisfaction with surgery (B).…”

Section: Discussionmentioning

confidence: 99%

Symptoms and Satisfaction of Patients in the Patient-Reported Outcomes With Laser In Situ Keratomileusis (PROWL) Studies

et al. 2017

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IMPORTANCE Patient-reported outcomes should be collected using validated questionnaires prior to and following laser in situ keratomileusis (LASIK) surgery.OBJECTIVE To report the frequency of patient-reported visual symptoms, dry eye symptoms, satisfaction with vision, and satisfaction with LASIK surgery in the Patient-Reported Outcomes With LASIK (PROWL) studies. DESIGN, SETTING, AND PARTICIPANTSThe PROWL-1 and PROWL-2 studies were prospective, observational studies conducted from September 13, 2011, to June 27, 2014. The PROWL-1 study was a single-military center study of 262 active-duty Navy personnel 21 to 52 years of age. The PROWL-2 study was a study of 312 civilians 21 to 57 years of age conducted at 5 private practice and academic centers. The LASIK surgery and the postoperative care were performed based on the usual practice and clinical judgment at the site. Participants completed a self-administered, web-based questionnaire, preoperatively and postoperatively at 1 and 3 months (the PROWL-1 and -2 studies) and at 6 months (the PROWL-2 study).EXPOSURES Participants underwent LASIK surgery for myopia, hyperopia, and/or astigmatism. MAIN OUTCOMES AND MEASURESVisual symptoms (double images, glare, halos, and/or starbursts), dry eye symptoms, participant satisfaction (with vision and LASIK surgery), and clinical measures (visual acuity, refractive error, and slitlamp and posterior segment eye examination findings) were assessed preoperatively and at 1, 3, and 6 months postoperatively.RESULTS A total of 262 participants were enrolled in the PROWL-1 study (mean [SD] age, 29.1 [6.1] years), and a total of 312 participants were enrolled in the PROWL-2 study (mean [SD] age, 31.5 [7.3] years). Visual symptoms and dissatisfaction with vision were common preoperatively. Overall, the prevalence of visual symptoms and dry eye symptoms decreased, although a substantial percentage of participants reported new visual symptoms after surgery (43% [95% CI, 31%-55%] from the PROWL-1 study and 46% [95% CI, 33%-58%] from the PROWL-2 study at 3 months). The percentages of participants in the PROWL-1 study with normal Ocular Surface Disease Index scores were 55% (95% CI, 48%-61%) at baseline, 66% (95% CI, 59%-72%) at 3 months, and 73% (95% CI, 67%-79%) at 6 months. The percentages of participants in the PROWL-2 study with normal Ocular Surface Disease Index scores were 44% (95% CI, 38%-50%) at baseline and 65% (95% CI, 59%-71%) at 3 months. Of those participants who had normal scores at baseline in both the PROWL-1 and -2 studies, about 28% (95% CI, 19%-37%) had mild, moderate, or severe dry eye symptoms at 3 months. While most participants were satisfied, the rates of dissatisfaction with vision ranged from 1% (95% CI, 0%-4%) to 4% (95% CI, 2%-7%), and the rates of dissatisfaction with surgery ranged from 1% (95% CI, 0%-4%) to 2% (95% CI, 1%-5%). CONCLUSIONS AND RELEVANCEThe systematic administration of a questionnaire to patients who have undergone LASIK surgery is a new approach to assess symptoms and satisfaction. Our findi...

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“…17 The syndrome is a common complication after corneal laser refractive surgery 18,19 and cataract surgery. 20,21 However, the common feature of the various manifestations of dryeye syndrome is an abnormal tear film; that is, irregular tear-film distribution across the corneal surface.…”

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confidence: 99%