In this study, we consider an holographic dark energy and dark matter interacting model in the Bianchi Type-V universe with a stretched exponential scale factor. We obtain the Hubble, shear, deceleration, and equation of state parameters based on the presented model and give the numerical solutions. We show that the anisotropy in the early universe plays an important role in the time evolution of the universe. Furthermore, we show that an interacting anisotropic model with stretched exponential scale factors can explain all epochs of the universe.