2024
DOI: 10.3390/cancers16081563
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Latest Insights and Therapeutic Advances in Myelodysplastic Neoplasms

Pasquale Niscola,
Valentina Gianfelici,
Marco Giovannini
et al.

Abstract: Myelodysplastic syndromes/neoplasms (MDSs) encompass a range of hematopoietic malignancies, commonly affecting elderly individuals. Molecular alterations in the hematopoietic stem cell compartment drive disease pathogenesis. Recent advancements in genomic profiling have provided valuable insights into the biological underpinnings of MDSs and have expanded therapeutic options, particularly for specific molecularly defined subgroups. This review highlights the diagnostic principles, classification updates, progn… Show more

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