Lathyrism and Aging

Yeager, Vernon L.

doi:10.3181/00379727-129-33246

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1971

1991

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Cited by 6 publications

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“…In the mature tissues as well, structure and function represent an inseparable unity. In our experiments BAPN-feeding did not produce alterations in the tissues of adult animals (in good agreement with the results of Yeager and Taylor [29] and others). In developing animals (young rabbits) characteristic al terations could be observed.…”

Section: Discussionsupporting

confidence: 81%

Changes in the Thermal Decomposition of Aorta, Tendon and Articular Cartilage in Experimental Lathyrism

Bihari-Varga¹,

Bı́ró²,

Lévai³

1971

Gerontology

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A thermal analytical method was applied to study the effect of experimental lathyrism on the composition and structural stability of aorta, tendon and hyaline cartilages of rabbits.A defect in collagen and elastin synthesis, resulting in the production of labile cross-linkages within the fibrillar protein moiety of the connective and vascular tissues of growing animals could be demonstrated. In the aorta and tendon of young rabbits glycosa4minoglycan concentration increased in the first 20 days of treatment. In the investigated tissues of adult animals β-amino-propionitrile-feeding caused no alterations.

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Section: Discussionsupporting

confidence: 81%