Lattice Boltzmann method simulations of swelling of cuboid-shaped IPN hydrogel tablets with experimental validation

Boschetti, Pedro J.; Toro, David J.; Ontiveros, Alejandro; Pelliccioni, Orlando; Sabino, Marcos A.

doi:10.1007/s00231-021-03132-8

Cited by 4 publications

(2 citation statements)

References 60 publications

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“…In the same year, the group [99] used computational simulations using the lattice Boltzmann method to complement the assessment of the swelling behavior of hydrogel samples of cylindrical and parallel hexagonal shapes. Later, Boschetti et al [100] utilized finite elements and FDM to simulate the free swelling of 3D hydrogels. Toro et al [101] computationally simulated the dehydration behavior of IPN (interpenetrating polymer network) hydrogel tablets.…”

Section: Research On Computational Fluid Dynamics Applied To Hydrogelmentioning

confidence: 99%

Advancements and Prospects of Hydrogel Sweat Cooling Technology in Multiphase Heat Transfer Applications: A Review

Xu,

Li,

et al. 2024

Energies

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Hydrogel sweat cooling is one of the leading areas in the study of multiphase heat transfer. In this study, the principles, applications, current research status, and future trends of hydrogel sweat cooling technology are comprehensively reviewed. By combing through and analyzing the relevant literature, the research progress in hydrogel sweat cooling is presented from the application perspective, including its use in electronic devices, buildings, and clean-energy facilities. The principle of each application is illustrated, the research status is established, and pros and cons are proposed. To provide inspiration for future research, the development trend is set out. Our literature review indicates that research on advanced hydrogels is the most promising research direction, including studies on the effect of environmental and indoor factors on sweat cooling performance through numerical, experimental, and theoretical means. Challenges for future research mainly include conducting hydrogel numerical analysis which can be experimentally verified, developing advanced hydrogels in a green way, and achieving the precise regulation of hydrogel control through intelligent methods. Interdisciplinary integration might be promising as well due to the fact that it can reveal the hydrogel sweat cooling mechanism from a different perspective. This study aims to promote multiphase cooling technology in exploring the application of hydrogels in energy utilization criteria.

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Section: Research On Computational Fluid Dynamics Applied To Hydrogelmentioning

confidence: 99%

Advancements and Prospects of Hydrogel Sweat Cooling Technology in Multiphase Heat Transfer Applications: A Review

Xu,

Li,

et al. 2024

Energies

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“…. Over the years, formulators have focused fabricated these IPNs into various dosage forms [15][16][17][18][19][20][21][22][23] . They have also made them smarter by making them respond to stimuli such as magnets 24 , temperature 25 , pH 26 , ions 27 , electrons 28 , and light 29 .…”

Section: Jordan Journal Of Pharmaceutical Sciences Volume 16 No 4 2023mentioning

confidence: 99%

Fabrication of Interpenetrating Polymer Network-Based Hydrogel for Colon-Targeted Release of Nateglinide

Kothiya,

Vaghani

2023

Jordan j. pharm. sci.

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Nateglinide is an anti-diabetic agent that experiences modest first-pass metabolism and poor aqueous solubility. This paper explores the preparation, characterization, and evaluation of interpenetrating polymer network composite hydrogels of chitosan and poly(meth(methacrylic)) acid as a potential carrier for the drug. Interpenetrating polymer network composite hydrogels of chitosan and poly(meth(methacrylic) acid incorporating nateglinide were prepared using N,Nꞌ-methylene bisacrylamide and glutaraldehyde as cross-linkers. The polymerization of chitosan, entrapment of the drug, and its interaction in prepared hydrogels were checked by FTIR spectroscopy, DSC, and powder XRD studies. The hydrogels were evaluated for their swelling behavior and in vitro drug release. The morphology of the hydrogels before and after dissolution was studied using SEM. The hydrogels showed a 93.29 ± 4.65% yield and 91.28 ± 2.22% drug loading. The hydrogels exhibited pH-sensitive swelling behavior. The in vitro release profile confirmed that the drug release depended on the swelling of hydrogels and showed a biphasic release pattern. Chitosan-poly(meth(methacrylic)) acid interpenetrating polymer network hydrogel, with its biodegradable nature and pH-sensitive release of nateglinide, is an attractive option to be further explored for targeted controlled drug delivery formulations for the drug.

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The Deswelling of IPN Hydrogel Tablets by Lattice Boltzmann Method

et al. 2023

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Lattice Boltzmann method simulations of swelling of cuboid-shaped IPN hydrogel tablets with experimental validation

Cited by 4 publications

References 60 publications

Advancements and Prospects of Hydrogel Sweat Cooling Technology in Multiphase Heat Transfer Applications: A Review

Advancements and Prospects of Hydrogel Sweat Cooling Technology in Multiphase Heat Transfer Applications: A Review

Fabrication of Interpenetrating Polymer Network-Based Hydrogel for Colon-Targeted Release of Nateglinide

The Deswelling of IPN Hydrogel Tablets by Lattice Boltzmann Method

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