Lax Prophylaxis: Vaccinating the Inflammatory Bowel Disease Patient

Gurvits, Grigoriy E.

doi:10.1007/s10620-017-4836-z

Cited by 3 publications

(19 citation statements)

References 10 publications

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“…However, compliance is low, and does not exceed 65% for any of the vaccines analysed. This observation coincides with the findings of several authors, who have reported suboptimal coverage levels in both primary care and hospital settings [15,25,38].…”

Section: Discussionsupporting

confidence: 92%

“…In the sanitary district of Lleida most patients with IBD are diagnosed in hospital settings, but vaccines are mainly administered by primary care practitioners and records are kept in the centralized ECAP database. Sometimes, patients do not visit their primary care centre for vaccination, and in other cases, insufficient or confusing information regarding their health status or their treatment is provided: approximately 50% of patients with IBD do not know that they need to be vaccinated against certain diseases [25]. This lack of awareness, together with other barriers that complicate compliance such as vaccination costs and incorrect or inadequate vaccination recommendations by healthcare professionals, must be addressed [25,39].…”

Section: Discussionmentioning

confidence: 99%

“…Interventions involving patient education and continuous training for healthcare professionals are needed to improve compliance among IBD patients [7,17,25,40], and standardized vaccination protocols are therefore essential for reducing vaccine-preventable infections and improving patient quality of life. In this sense, in 2018 the Spanish Ministry of Health, Consumption, and Social Wellbeing published vaccination recommendations for patients of all ages at risk of vaccine-preventable diseases, which included specific protocols for IBD [41].…”

Section: Discussionmentioning

confidence: 99%

“…In other studies, IBD patients under treatment with infliximab and immunomodulatory therapy showed an impaired response to a single dose of trivalent inactivated influenza vaccine [22,23]. For this reason, and due to their increased risk of opportunistic infections in the first year of immunosuppressive therapy, IBD patients should be vaccinated as soon as possible after diagnosis [1,15,24,25]. Prevention of infectious disease in this population is a public health issue and vaccination may be an effective tool.…”

Section: Introductionmentioning

confidence: 99%

“…Although the access to vaccination is free and universal in Spain and many infections can be prevented by vaccination, coverage in clinical practice remains uncertain. Better communication between practitioners working at different levels of care is essential to prevent under-recording and under-immunization [1,25].…”

Section: Introductionmentioning

confidence: 99%

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Compliance with the guidelines on recommended immunization schedule in patients with inflammatory bowel disease: implications on public health policies

et al. 2020

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Background: Patients with inflammatory bowel disease (IBD) have a higher risk of developing opportunistic infections due to either the disease itself or to treatment with immunosuppressants. This risk can be reduced through vaccination. The aim of this study was to determine the prevalence of compliance with the guidelines on recommended immunization schedule in patients with IBD in the health district of Lleida, Spain. Methods: Descriptive, cross-sectional, retrospective study of data at December 31, 2016. The reference population was formed by adults with a clinical diagnosis of IBD. The dependent variable was "compliance with the guidelines on recommended immunization schedule". Variables were sex, age, residence, diagnosis, vaccination against measles, mumps, rubella, varicella, tetanus-diphtheria, influenza, pneumococcus, meningococcus C, hepatitis B, and hepatitis A. Data were obtained from electronic medical records. For the data analysis, mean (standard deviation), prevalence with 95% confidence intervals, χ 2 test and Mann-Whitney test were used. Results: Compliance did not exceed 65% for any of vaccines analysed in the 1722 studied patients with ulcerative colitis or Crohn's disease. Significant differences across age groups were found in compliance for measles, mumps, rubella, varicella, tetanus, diphtheria and influenza in both ulcerative colitis and Crohn's disease and for meningococcus C and hepatitis A exclusively in ulcerative colitis. Conclusions: Compliance in patients with IBD is low. Thus, prevention of immunopreventable diseases or their complications is not maximized in this kind of patients. Greater awareness of how vaccines can reduce the risk of vaccine-preventable infections is needed among both patients and healthcare professionals.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Compliance with the guidelines on recommended immunization schedule in patients with inflammatory bowel disease: implications on public health policies

et al. 2020

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Vaccines – beliefs and concerns: the voice of patients with inflammatory immunomediated diseases

Abreu

Martins

Branco

et al. 2023

European Journal of Gastroenterology &Amp; Hepatology

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Background Vaccination is a key issue in patients with immunomodulated inflammatory diseases on immune-mediated therapy. Still, vaccination rates in these patients are low. This study aimed to assess the knowledge and fears of patients with immune-mediated inflammatory diseases (IMIDs) regarding vaccines, with the ultimate goal of increasing vaccination rates through the definition and implementation of more effective communication strategies with the patient. Methods This study was conducted in a Portuguese hospital, between January 2019-December 2020, and included adult patients with an IMID. A questionnaire was developed and applied to evaluate knowledge and fears regarding vaccines. Results From the 275 included patients, more than 90% answered correctly to all questions on general knowledge, with an exception for the question related to protection from severe disease, without differences between age groups or education levels, except for the question about vaccine contraindications (P = 0.017). Regarding vaccines in immunocompromised hosts, the proportion of correct answers was lower and significantly different between education levels (P = 0.00–0.042),. More than 50% of the participants showed moderate to very high concern about several aspects of vaccines, with differences between age groups (P = 0.018). Conclusion Our patients have general knowledge of vaccines but regarding vaccines in immunocompromised patients knowledge is lower and dependent on the education level. In addition, age influences the pattern of concerns related to vaccines. The information gathered in this study shall be considered to identify potential local interventions targeted to improve vaccination.

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Impact of an Intervention to Promote the Vaccination of Patients with Inflammatory Bowel Disease

García-Serrano,

Artigues-Barberà,

Mirada

et al. 2023

Vaccines

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Patients with inflammatory bowel disease (IBD) have a dysregulated immune system, being at high risk of opportunistic infections. Low vaccination rates hinder the prevention of such diseases. Therefore, we implemented an intervention to increase vaccination rates, and we aimed to evaluate the effect. We determined the change in professionals and the change in the vaccination rates after the intervention. A quasi-experimental study was carried out using data from 31 December 2016 to 31 December 2021. First, healthcare professionals specializing in IBD agreed on a vaccination protocol; then, this protocol was passed on to the professionals involved in vaccination. We evaluated the perception of knowledge, capacity, and intention to vaccinate patients with IBD among the professionals before and after the intervention with a survey. We also described the effectiveness of the intervention for already diagnosed patients and compared the vaccination rates between patients diagnosed prior to the intervention and newly diagnosed patients. The intervention resulted in an improved perception of knowledge, capacity, and intention to vaccinate patients with IBD among the professionals (p < 0.05). Moreover, during the post-intervention period, in the 315 patients, the vaccination rate increased for all immune-preventable diseases (p < 0.05). The professionals positively valued the intervention, and compliance with the recommended vaccination protocol in patients with IBD improved significantly.

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Lax Prophylaxis: Vaccinating the Inflammatory Bowel Disease Patient

Cited by 3 publications

References 10 publications

Compliance with the guidelines on recommended immunization schedule in patients with inflammatory bowel disease: implications on public health policies

Compliance with the guidelines on recommended immunization schedule in patients with inflammatory bowel disease: implications on public health policies

Vaccines – beliefs and concerns: the voice of patients with inflammatory immunomediated diseases

Impact of an Intervention to Promote the Vaccination of Patients with Inflammatory Bowel Disease

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