Layered Double Hydroxide-Based Nanomaterials-From Fundamentals to Applications

Szilágyi, István

doi:10.3390/nano9081174

Cited by 4 publications

(4 citation statements)

References 15 publications

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“…(1−x) Al 3+ x (OH) 2 ] x+ (A n− ) x/n •yH 2 O are interesting materials for photo-, electro-, and thermocatalysis [1,2] and electronic applications [3][4][5]. They typically adopt three-dimensional, lamellar structures of mixed metal oxyhydroxide platelets, with the interlayer voids providing nanoporous chemical reactors [6].…”

Section: Layered Double Hydroxides (Ldh) Of General Formula [M 2+mentioning

confidence: 99%

Alkali-Free Hydrothermally Reconstructed NiAl Layered Double Hydroxides for Catalytic Transesterification

et al. 2022

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NiAl layered double hydroxides (LDHs) are promising bifunctional catalysts comprising tunable redox and Lewis acidic sites. However, most studies of NiAl LDH employ alkali hydroxide carbonate precipitants which may contaminate the final LDH catalyst and leach into reaction media. Here, we report an alkali-free route to prepare NixAl LDHs with a composition range x = 1.7 to 4.1 using (NH4)2CO3 and NH4OH as precipitants. Activation of LDHs by calcination–rehydration protocols reveal NixAl LDHs can be reconstructed under mild hydrothermal treatment (110 °C for 12 h), with the degree of reconstruction increasing with Ni content. Catalyst activity for tributyrin transesterification with methanol was found to increase with Ni content and corresponding base site loadings; TOFs also increased, suggesting that base sites in the reconstructed LDH are more effective for transesterification. Hydrothermally reconstructed Ni4.1Al LDH was active for the transesterification of C4–C12 triglycerides with methanol and was stable towards leaching during transesterification.

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Section: Layered Double Hydroxides (Ldh) Of General Formula [M 2+mentioning

confidence: 99%

Alkali-Free Hydrothermally Reconstructed NiAl Layered Double Hydroxides for Catalytic Transesterification

et al. 2022

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“…The compositional variety, lamellar structure, and biocompatibility characteristics of LDHs, together with their simplicity for larger scale synthesis attracted the interest of many groups in the field. 99 …”

Section: The Role Of Ceftriaxone Nanostructures In Countering Amrmentioning

confidence: 99%

“…Layered double hydroxides (LDHs) and their complexes with several materials offer a key group of resources suitable for a number of current and future uses for biochemical and environmental developments. The compositional variety, lamellar structure, and biocompatibility characteristics of LDHs, together with their simplicity for larger scale synthesis attracted the interest of many groups in the field 99 …”

Section: The Role Of Ceftriaxone Nanostructures In Countering Amrmentioning

confidence: 99%

The contribution of nano‐based strategies in overcoming ceftriaxone resistance: a literature review

Yayehrad

Marew

Birhanu

2021

Pharmacology Res & Perspec

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Antimicrobial drug resistance, including resistance to multiple antibiotics, is continuously increasing. According to research findings, many bacteria resistant to other antibiotics were susceptible to ceftriaxone. However, over the last few years, ceftriaxone resistance has become growing and extremely worrisome challenge to the global healthcare system and several strategies have been initiated to contain the spread of antimicrobial drug resistance. Its extended use for therapeutic or preventative measures in humans and farm animals resulted in the development and spread of resistance. Recent advances in nanotechnology also offer novel formulations based on distinct types of nanostructure particles with different sizes and shapes, and flexible antimicrobial properties. For ceftriaxone, several nanostructured formulations through conjugation, intercalation, encapsulation with lipid carrier, and polymeric films have been investigated by different groups with promising results in combating the development of resistance. This review addressed the existing knowledge and practice on the contribution of nano‐based delivery approaches in overcoming ceftriaxone resistance. Evidences have been generated from published research articles using major search electronic databases such as PubMed, Medline, Google Scholar, and Science Direct.

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“…Sepsis is a serious life-threatening disease caused by infection, and is mainly characterized by an inflammatory response Recently, various nanotechnology methods have been applied as novel strategies in biomedicine. [13][14][15][16][17] Sheet-like layered double hydroxide (LDH) nanoparticles are a highly biocompatible family of clay nanomaterials, [18,19] with potential in biological applications owing to their customizability (of elements on the laminate), high loading capacities (through anion exchange), facilitation of cellular uptake of delivered drugs, [20,21] acidity-triggered drug release, low toxicity, and good biocompatibility. [22][23][24] They are reported to be self-degrading via slow dissolution at the disease site (pH 6-7) and release some free ions (such as Mg 2+ , Al 3+ , and Cl − ) or tiny hydroxide nanodots (such as "Al(OH)3") during and after the loaded drug has been completely released, [25] which have low toxicity, especially at the low dose.…”

Section: Introductionmentioning

confidence: 99%

Improved Anticoagulant Effect of Layered Double Hydroxide‐Heparin Nanocomposites on the Microcirculation of Septic Rats

Mao

Shan

Wang

et al. 2022

Advanced Therapeutics

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Anticoagulant therapy is an important therapeutic tool for septic microcirculatory dysfunction. Low molecular weight heparin (LMWH) is a potent anticoagulant with antithrombotic properties, which is a crucial factor for sepsis treatment. However, it has a short plasma half-life and achieves low local concentrations; nanocomposite formulations may help overcome these limitations. Herein, it is aimed to determine if a functional layered double hydroxide (LDH)-LMWH nanocomposite improves microcirculation and organ function, while maximizing the antithrombotic effects and reducing bleeding risks in septic rats. This nanocomposite (fluorescein isothiocyanate (FITC)-fibrin antibody (Ab)-bovine serum albumin (BSA)-20LMWH-LDH) is constructed by intercalating LMWH and FITC into the LDH interlayer, and application of a BSA and an Ab coating onto the LDH nanoparticle surface. The nanocomposite released LMWH in a gradual and biphasic pattern, in an acidity-triggered manner. Capillary tubule studies and intestinal microcirculation investigations show that green fluorescent nanocomposites accumulated around microthrombi, validating their targeting ability. Animal experiments reveal that the nanocomposites significantly improve microcirculation in septic rats with minimal pathological damage to the heart, lung, liver, and kidney tissues. Thus, this study provides a novel strategy for the treatment of septic microcirculatory dysfunction in clinical situations.

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Layered Double Hydroxide-Based Nanomaterials-From Fundamentals to Applications

Abstract: Layered double hydroxides (LDHs) and their composites with various substances represent an important class of materials suitable for several existing and future applications in biological, chemical, and environmental processes [...]

Cited by 4 publications

References 15 publications

Alkali-Free Hydrothermally Reconstructed NiAl Layered Double Hydroxides for Catalytic Transesterification

Alkali-Free Hydrothermally Reconstructed NiAl Layered Double Hydroxides for Catalytic Transesterification

The contribution of nano‐based strategies in overcoming ceftriaxone resistance: a literature review

Improved Anticoagulant Effect of Layered Double Hydroxide‐Heparin Nanocomposites on the Microcirculation of Septic Rats

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