Layered MoS2 nanosheets modified by biomimetic phospholipids: Enhanced stability and its synergistic treatment of cancer with chemo-photothermal therapy

Xie, Meng; Yang, Na; Cheng, Jiaxi; Yang, Mei; Deng, Tongtong; Li, Yeping; Feng, Chunlai

doi:10.1016/j.colsurfb.2019.110631

Cited by 33 publications

(12 citation statements)

References 34 publications

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“…223,224 A nice strategy to mitigate these issues, improve the biocompatibility and decrease even more the cytotoxicity is to perform the functionalization of the surface of Mos 2 with biocompatible materials and/or biomolecules. This was clearly demonstrated recently by Xie M. et al 225 The authors showed the modification of the MoS 2 surface with egg yolk phospholipids (MoS 2 -lipid) to enhance the stability of the MoS 2 nanosheets under physiological conditions and to act as a nanocarrier system for the treatment of tumors via the combination of chemotherapy and photothermal therapy. The MoS 2 -lipid demonstrated a loading rate of DOX of 104.4%, and a release mediated by pH and NIR light.…”

Section: Biomedicalmentioning

confidence: 67%

Recent advancement in biomedical applications on the surface of two-dimensional materials: from biosensing to tissue engineering

2020

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Section: Biomedicalmentioning

confidence: 67%

Recent advancement in biomedical applications on the surface of two-dimensional materials: from biosensing to tissue engineering

2020

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“…2D black phosphorus (BP) nanosheets, as typical semiconductor like graphene, [ 353–355 ] MoS 2 , [ 356–359 ] or WS 2 , [ 123 ] and Mxene, [ 225 ] has tunable bandgap and unique optical property to determine its application in cancer PTT. [ 360 ] Ultrahigh surface area to volume ratio provides plenty of anchoring points for anticancer drugs to make them ideal nanocarrier in drug delivery systems.…”

Section: Nir‐ii Ptt For Cancermentioning

confidence: 99%

“…Especially, the 2D composites exhibited high sensitivity of fluorescence imaging, PA imaging, and photothermal imaging, indicating it can be used for deep solid cancer diagnosis therapy. For their further clinical translation, simple preparation strategies SnTebased theranostics nanoplatform need to be further developed for high NIR II-mediated clinical potential for cancer theranostics to overcome some possible complex preparation process 2D black phosphorus (BP) nanosheets, as typical semiconductor like graphene, [353][354][355] MoS 2 , [356][357][358][359] or WS 2 , [123] and Mxene, [225] has tunable bandgap and unique optical property to determine its application in cancer PTT. [360] Ultrahigh surface area to volume ratio provides plenty of anchoring points for anticancer drugs to make them ideal nanocarrier in drug delivery systems.…”

Section: Ptt Combined Chemotherapymentioning

confidence: 99%

NIR‐II Responsive Inorganic 2D Nanomaterials for Cancer Photothermal Therapy: Recent Advances and Future Challenges

Zhang

et al. 2021

Adv Funct Materials

173

102

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Non‐invasive cancer photothermal therapy (PTT) is a promising replacement for traditional cancer treatments. The second near‐infrared region induced PTT (NIR‐II PTT, 1000–1500 nm) with less energy dissipation has been developed for deeper‐seated tumor treatment in recent years compared with the traditional first near‐infrared light (750–1000 nm). In addition, the use of emerging inorganic 2D nanomaterials as photothermal agents (PTAs) further enhanced PTT efficiency due to their intrinsic photothermal properties. NIR‐II light stimulated inorganic 2D nanomaterials for PTT is becoming a hot topic in both academic and clinical fields. This review summarizes the categories, structures, and photothermal conversion properties of inorganic 2D nanomaterials for the first time. The recent synergistic strategies of NIR‐II responsive PTT combined with other treatment approaches including chemotherapy, chemodynamic therapy, photodynamic therapy, radiotherapy are summarized. The future challenges and perspectives on these 2D nanomaterials for NIR‐II responsive PTT systems construction are further discussed.

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“…16 b-f). Furthermore, studies demonstrated that MoS 2 nanosheets modified by chitosan [ 237 ], hyperbranched polyglycidyl (HPG) [ 325 ] or egg yolk phospholipids [ 326 ] could also serve as nanoplatforms with good colloidal stability and biocompatibility to realize the synergistic treatment of chemotherapy and PTT. Time-staggered administration of erlotinib (Er) and DOX can enhance the anticancer effect, but its clinical application is limited due to different administration routes and formulation parameters.…”

Section: Multifunctional Nanoplatforms For Cancer Therapymentioning

confidence: 99%

MoS2-based nanocomposites for cancer diagnosis and therapy

Wang

Li-hua

Huang

et al. 2021

Bioactive Materials

149

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Molybdenum is a trace dietary element necessary for the survival of humans. Some molybdenum-bearing enzymes are involved in key metabolic activities in the human body (such as xanthine oxidase, aldehyde oxidase and sulfite oxidase). Many molybdenum-based compounds have been widely used in biomedical research. Especially, MoS 2 -nanomaterials have attracted more attention in cancer diagnosis and treatment recently because of their unique physical and chemical properties. MoS 2 can adsorb various biomolecules and drug molecules via covalent or non-covalent interactions because it is easy to modify and possess a high specific surface area, improving its tumor targeting and colloidal stability, as well as accuracy and sensitivity for detecting specific biomarkers. At the same time, in the near-infrared (NIR) window, MoS 2 has excellent optical absorption and prominent photothermal conversion efficiency, which can achieve NIR-based phototherapy and NIR-responsive controlled drug-release. Significantly, the modified MoS 2 -nanocomposite can specifically respond to the tumor microenvironment, leading to drug accumulation in the tumor site increased, reducing its side effects on non-cancerous tissues, and improved therapeutic effect. In this review, we introduced the latest developments of MoS 2 -nanocomposites in cancer diagnosis and therapy, mainly focusing on biosensors, bioimaging, chemotherapy, phototherapy, microwave hyperthermia, and combination therapy. Furthermore, we also discuss the current challenges and prospects of MoS 2 -nanocomposites in cancer treatment.

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Layered MoS2 nanosheets modified by biomimetic phospholipids: Enhanced stability and its synergistic treatment of cancer with chemo-photothermal therapy

Cited by 33 publications

References 34 publications

Recent advancement in biomedical applications on the surface of two-dimensional materials: from biosensing to tissue engineering

Recent advancement in biomedical applications on the surface of two-dimensional materials: from biosensing to tissue engineering

NIR‐II Responsive Inorganic 2D Nanomaterials for Cancer Photothermal Therapy: Recent Advances and Future Challenges

MoS2-based nanocomposites for cancer diagnosis and therapy

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