Find alternative compounds to control two spotted red spider mite, Tetranychus urticae Koch, in Squash is very important to protect squash and to avoid the problems could be occurred due to the extensive usage of conventional acaricides. The plant extracts camphor, menthol, thymol and citric acid efficiency against T. urticae was tested under field condition in comparing with acetamiprid and azadirachta indica (Neem). The results revealed that during 2018 winter season there were significant differences as a primary effect in between the tested compounds, where the highest reduction rate among the plant extracts tested after one day of treatment was recorded with citric acid 88.5%. The tested compounds also showed good efficiency after three, five and seven days of treatment as a residual effect. There were no significant differences found between the tested compounds and the standard compounds. The highest reduction rates were recorded for azadirachtin and acetamiprid 93.87%, 90 %., respectively. Whereas, in case of the tested plant extracts, the highest reduction rates were observed for the camphor 88.97 % followed by menthol 88.13%. The results also indicated that during the summer season 2019 significant differences after one day of spraying as initial effect of the tested compounds were detected. The highest rates of reduction were as follow: 89.51, 85.70, 82.63 and 81.25% for citric acid, menthol, thymol and camphor compared to 95.97 and 93 .84% reduction achevied by azadirachtin and acetamiprid as standard treatments respectively.