Learning to control tinnitus

Husain, Fatima T.

doi:10.1016/bs.plm.2021.02.002

Cited by 3 publications

(1 citation statement)

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“…Combinations of tinnitus sounds (e.g., ringing and buzzing or buzzing and whooshing) cause significantly more impairment than a single percept [ 6 ]. Although tinnitus is a common, functionally disabling condition that has been described in the medical literature for millenia [ 7 , 8 ], the neurobiology of tinnitus remains unsolved. Over roughly the past two decades, a modest body of neuroimaging studies has emerged seeking to address this shortcoming.…”

Section: Introductionmentioning

confidence: 99%

Invariant structural and functional brain regions associated with tinnitus: A meta-analysis

Moring

Husain²,

Gray³

et al. 2022

PLoS ONE

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Tinnitus is a common, functionally disabling condition of often unknown etiology. Neuroimaging research to better understand tinnitus is emerging but remains limited in scope. Voxel-based physiology (VBP) studies detect tinnitus-associated pathophysiology by group-wise contrast (tinnitus vs controls) of resting-state indices of hemodynamics, metabolism, and neurovascular coupling. Voxel-based morphometry (VBM) detects tinnitus-associated neurodegeneration by group-wise contrast of structural MRI. Both VBP and VBM studies routinely report results as atlas-referenced coordinates, suitable for coordinate-based meta-analysis (CBMA). Here, 17 resting-state VBP and 8 VBM reports of tinnitus-associated regional alterations were meta-analyzed using activation likelihood estimation (ALE). Acknowledging the need for data-driven insights, ALEs were performed at two levels of statistical rigor: corrected for multiple comparisons and uncorrected. The corrected ALE applied cluster-level inference thresholding by intensity (z-score > 1.96; p < 0.05) followed by family-wise error correction for multiple comparisons (p < .05, 1000 permutations) and fail-safe correction for missing data. The corrected analysis identified one significant cluster comprising five foci in the posterior cingulate gyrus and precuneus, that is, not within the primary or secondary auditory cortices. The uncorrected ALE identified additional regions within auditory and cognitive processing networks. Taken together, tinnitus is likely a dysfunction of regions spanning multiple canonical networks that may serve to increase individuals’ interoceptive awareness of the tinnitus sound, decrease capacity to switch cognitive sets, and prevent behavioral and cognitive attention to other stimuli. It is noteworthy that the most robust tinnitus-related abnormalities are not in the auditory system, contradicting collective findings of task-activation literature in tinnitus.

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Section: Introductionmentioning

confidence: 99%

Invariant structural and functional brain regions associated with tinnitus: A meta-analysis

Moring

Husain²,

Gray³

et al. 2022

PLoS ONE

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Treatment of Posttraumatic Stress Disorder Alleviates Tinnitus-Related Distress Among Veterans: A Pilot Study

et al. 2022

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Purpose: Military service personnel are at increased risk for developing tinnitus due to heightened exposure to acoustic trauma. The auditory disorder is the leading service-connected disability among veterans and is highly comorbidly diagnosed with posttraumatic stress disorder (PTSD). The biopsychosocial model illustrates that chronic health conditions are exacerbated or maintained by psychiatric distress. Therefore, alleviation of such psychiatric distress can have beneficial impacts on health conditions, such as tinnitus. The aim of this study was to determine whether individuals with both disorders who receive evidence-based therapy for PTSD will experience decreases in both PTSD and tinnitus-related distress. Method: Veterans with comorbid bothersome tinnitus and PTSD received cognitive processing therapy and were assessed for PTSD, tinnitus-related distress, and depression at baseline and 1 month posttreatment follow-up. Results: At posttreatment follow-up, participants demonstrated significant decreases in PTSD symptoms compared to their baseline scores. Participants also demonstrated decreased tinnitus-related distress and depression, with high effect sizes. Conclusions: This pilot study demonstrated that clinical management addressing psychiatric distress, as associated with PTSD, may simultaneously provide benefit for patients with bothersome tinnitus. Although not statistically significant due to the small sample size, large effect sizes indicate that tinnitus-related distress decreased as a function of receiving evidence-based therapy for PTSD. Future clinical trials should increase sample sizes and compare effects to control conditions.

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An Experimental Approach to Measure the Impact of Musical Logos on Brand Equity

Sharma

Mahendran

Balasudarsun³

2023

Global Business Review

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Using musical logos (MLs; jingles) for brand promotion is a time-tested marketing strategy to develop brand recognition and aid memorability among consumers. The researchers adopted an experimental approach to measure the impact of MLs on brand equity (BE) for the Fast Moving Consumable Goods (FMCG) companies. The study is based on empirical evidence collected through an online survey featuring audio media circulated through referrals among ( n = 632) end consumers of 25 popular brands of FMCG companies in India. Correlation and regression analysis were used to measure the cause-and-effect relationship between MLs and BE by developing brand awareness (BAW) and creating favourable brand associations (BASs). The results of the study reflect that consumers showed high BAW and positive associations regarding FMCG brands, which employed MLs in their promotions. It can be stated that there exists a positive relationship between the use of MLs and generation of BE. The study offers further suggestions to effectively utilize the potential of MLs in business.

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Learning to control tinnitus

Cited by 3 publications

References 169 publications

Invariant structural and functional brain regions associated with tinnitus: A meta-analysis

Invariant structural and functional brain regions associated with tinnitus: A meta-analysis

Treatment of Posttraumatic Stress Disorder Alleviates Tinnitus-Related Distress Among Veterans: A Pilot Study

An Experimental Approach to Measure the Impact of Musical Logos on Brand Equity

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