Left atrial appendage closure after cryoballoon ablation in patients with atrial fibrillation

Li, Jun; Xia, Yu; Zhang, Hao; Li, Xiaofeng; Zhang, Shu; Fang, Pihua

doi:10.1007/s00059-019-04880-4

Cited by 9 publications

(3 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The flowchart of the study selection process was shown in Figure 1. In total, 16 studies were included, 13,[27][28][29][30][31][32][33][34][35][36][37][38][39][40][41] and one of the studies was divided into two arms for meta-analysis according to the procedural strategies (First LAAC then RFA or First FRA then LAAC), 35…”

Section: Study Selection and Characteristicsmentioning

confidence: 99%

The long‐term efficacy and safety of combining ablation and left atrial appendage closure: A systematic review and meta‐analysis

Sun

et al. 2021

Cardiovasc electrophysiol

View full text Add to dashboard Cite

Background: Combined ablation and left atrial appendage closure (LAAC) is an alternative for atrial fibrillation patients with a high risk of stroke. However, the long-term outcomes of this combined procedure remain elusive.Methods: PubMed, Embase, Cochrane Library, and Web of Science were systematically searched from the establishment of databases to 1 January 2021. Studies on the long-term (defined as a mean follow-up of approximately 12 months or longer) efficacy and safety outcomes of combined ablation and LAAC were included.Results: A total of 16 studies comprising 1428 patients were enrolled. The pooled long-term freedom rate from atrial arrhythmia was 0.66 (95% confidence interval[CI]: 0.59-0.71), long-term successful rate sealing of LAAC was 1.00 (95% CI:1.00-1.00), and ischemic stroke/transient ischemic attack/systemic embolism during follow-up was 0.01 (95% CI: 0.00-0.02). Meanwhile, of the periprocedural adverse events, phrenic nerve palsy, intracoronary air embolus, device embolization, and periprocedural death had a rate of 0.00 (95% CI: 0.00-0.00), procedure-related bleeding events of 0.03 (95% CI: 0.02-0.04), and pericardial effusion requiring or not requiring intervention of 0.00 (95% CI: 0.00-0.01). Moreover, for the long-term adverse events, device dislocation, intracranial bleeding, pericardial effusion requiring or not requiring intervention, and all-cause mortality had a rate of 0.00 (95% CI: 0.00-0.00), device embolization of 0.01 (95% CI: 0.00-0.01), and other bleeding events of 0.01 (95% CI: 0.00-0.03). Conclusion:This meta-analysis suggests that the combined atrial ablation and LAAC is an effective and safe strategy with long-term benefits.

show abstract

Section: Study Selection and Characteristicsmentioning

confidence: 99%

The long‐term efficacy and safety of combining ablation and left atrial appendage closure: A systematic review and meta‐analysis

Sun

et al. 2021

Cardiovasc electrophysiol

View full text Add to dashboard Cite

show abstract

“…Exclusion of LAA using different techniques including surgical excision, epicardial snare or clip has shown similar benefit [21][22][23]. A recent strategy that has been gaining momentum called 'one-stop' procedure combing AF ablation and LAAE using endocardial closure device has shown to be feasible and safe [24][25][26]. Conflicting results have not clearly demonstrated an added value of such combined procedures in terms of maintaining sinus rhythm.…”

Section: Left Atrial Appendage Exclusion May Improve the Outcome Of A...mentioning

confidence: 99%

Exclusion of left atrial appendage: effects beyond thromboembolic prevention

Bai

Zawaneh

Weiss

et al. 2021

Current Opinion in Cardiology

View full text Add to dashboard Cite

Purpose of reviewThis review aims to summarize the nonthromboembolic prevention effects of left atrial appendage exclusion (LAAE). Recent findingsLeft atrial appendage (LAA) secretes multiple hormones; regulates blood volume and pressure; and generates trigger activities. Exclusion of the LAA by different techniques may lead to downstream effects including changes in blood pressure and cardiac performance, improvement of outcome of atrial fibrillation (AF) ablation, and alteration of metabolism. SummaryLAAE procedures not only prevent thromboembolic events in patients with AF, but rather may bring additional benefits or side-effect to patients undergoing LAAE.

show abstract

“…AF is a major risk factor for developing ischemic stroke and accounts for 15% of all strokes in the US [3,4]. Catheter ablation (CA) has been established as a safe and effective technique for the management of drug-refractory AF [5,6]. There have been multiple clinical trials comparing AF CA with antiarrhythmic drugs including Radiofrequency Ablation vs Antiarrhythmic Drugs as First-Line Treatment of Paroxysmal Atrial Fibrillation (RAAFT-2) trial [7], Early Aggressive Invasive Intervention for Atrial Fibrillation (Early-AF) trial [8], and Catheter Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation (CABANA) trial [9].…”

Section: Introductionmentioning

confidence: 99%

Incidental Cardiac Computed Tomography Findings in Patients Undergoing Atrial Fibrillation Catheter Ablation

Hamed¹,

Kloosterman²,

Berkowitz³

et al. 2022

Cureus

View full text Add to dashboard Cite

Background: Catheter ablation (CA) is an effective technique for the management of atrial fibrillation (AF). Cardiac computed tomography (CCT) is a non-invasive imaging modality that is used as a crucial part of planning before CA procedures which can detect other incidental findings and require further diagnostic investigations.Objectives: We sought to assess the prevalence and distribution of incidental CCT findings in patients with AF undergoing CA.Methods: Retrospective analysis over a three-year period (2013-2016) of 218 patients undergoing CCT prior to AF CA. CCT findings were analyzed and incident clinically important findings were reported.Results: Over the three-year period, 218 patients had undergone CCT. Of these, 28.8% showed clinically significant incidental findings in the chest and upper abdomen. Incidental findings included coronary artery disease (CAD), incomplete cor triatriatum, pericardial effusion, pleural effusion, pulmonary nodules, pulmonary infiltrates, pulmonary mass, thoracic aortic aneurysm, mediastinal nodes, abdominal mass, and liver nodules.Conclusions: CCT is a cornerstone investigation prior to AF CA and can show multiple incidental findings, thus potentially functioning as a screening method for the detection of other significant conditions. There is still a debate whether further workup is needed or not as most findings will eventually be benign and further investigations could mean financial burden and clinical risks to the patients. Further larger prospective studies are needed with long-term follow-up to determine whether incidental findings on CCT have an impact on the long-term outcomes of patients.

show abstract

Left atrial appendage closure after cryoballoon ablation in patients with atrial fibrillation

Cited by 9 publications

References 17 publications

The long‐term efficacy and safety of combining ablation and left atrial appendage closure: A systematic review and meta‐analysis

The long‐term efficacy and safety of combining ablation and left atrial appendage closure: A systematic review and meta‐analysis

Exclusion of left atrial appendage: effects beyond thromboembolic prevention

Incidental Cardiac Computed Tomography Findings in Patients Undergoing Atrial Fibrillation Catheter Ablation

Contact Info

Product

Resources

About