Left Atrial Functional Remodeling in Lone Atrial Fibrillation: A Two‐Dimensional Speckle Tracking Echocardiographic Study

Hong, Jing; Gu, Xiaoyan; An, Ping; Luo, Taiyang; Lv, Qiang; Kang, Jia; He, Yihua; Hu, Rong; Liu, Xiaohui; Ma, Changsheng

doi:10.1111/echo.12200

Cited by 31 publications

(31 citation statements)

References 34 publications

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“…This notion is supported by another recent report in which global LA strain at late diastole was shown to be a predictor of early AF recurrence after catheter ablation. 15 It should be noted that LA volume was not a statistically significant predictor of AF recurrence after catheter ablation in either study, suggesting that functional LA remodeling may be more sensitive than structural LA remodeling in predicting the outcome of AF ablation.…”

Section: Article P 1695mentioning

confidence: 63%

Can We Predict the Outcome of Catheter Ablation for Atrial Fibrillation?

Miyasaka

2013

Circ J

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Section: Article P 1695mentioning

confidence: 63%

Can We Predict the Outcome of Catheter Ablation for Atrial Fibrillation?

Miyasaka

2013

Circ J

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“…Previous reports have shown that some disease (hypertension, atrial fibrillation, coronary artery disease, etc.) may lead to left atrial phasic dysfunction evaluated by 2D-STE [22, 23]. Additionally, the longitudinal strain and strain rate, which are inversely related to LA wall fibrosis, have been reported to be a feasible and reproducible method to assess LA myocardial function [24, 25].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of left atrial function in patients with iron-deficiency anemia by two-dimensional speckle tracking echocardiography

Shen

Zhou

Liu

et al. 2015

Cardiovasc Ultrasound

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BackgroundIron-deficiency anemia (IDA) is a global health problem and a common medical condition that can be seen in everyday clinical practice. And two-dimensional speckle tracking echocardiography (2D-STE) has been reported very useful in evaluating left atrial (LA) function, as well as left ventricular (LV) function. The aim of our study is to evaluate the LA function in patients with IDA by 2D-STE.Methods65 patients with IDA were selected. This group of patients was then divided into two groups according to the degree of hemoglobin: group B (Hb > 90 g/L) and group C (Hb60 ~ 90 g/L). Another 30 healthy people were also selected as control group A. Conventional echocardiography parameters, such as left atrial diameter (LAD), peak E and A of mitralis (E, A), E/A, end-diastolic thickness of ventricular septum (IVST d), end-diastolic thickness of LV posterior wall (PWTd) and left ventricular end-diastolic dimension (LVDd) were obtained from these three groups. Left atrial minimum volume (LAVmin), left atrial pre-atrial contraction volume (LAVp) and left atrial maximum volume (LAVmax) were measured by Simpson’s rule, whereas left atrial active ejection fraction (LAAEF) and left atrial passive ejection fraction (LAPEF) were obtained from calculation. Two-dimensional images were acquired from apical four-chamber view and two-chamber view to store images for offline analysis. The global peak atrial longitudinal strain and strain rate of systolic LV (GLSs, GLSRs) as well as early and late diastolic LV strain rate (GLSRe, GLSRa) curves of LA were acquired in each LA segment from basal segment to top segment of LA by 2D-STE.ResultsCompared with group A, there were no differences between group B and group A (all P > 0.05). The LAAEF and GLSRa were significantly higher in group C compared with those of group A and group B (all P < 0.01). The LAPEF, GLSs, GLSRs and GLSRe were significantly lower in group C compared with those of group A and group B (all P < 0.01).Conclusions2D-STE could evaluate the LA function in patients with IDA.

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“…STE analysis has been demonstrated to be a feasible method to assess global and phasic LA longitudinal strains and strain rates in healthy subjects and in patients with LA dysfunction. [16][17][18][19] SRs has been used as an index of LA reservoir function, 27 while SRe and SRa are accepted as indices of LA conduit and LA contractile function, respectively. 9,28,30 In our study, both global and segmental systolic strains were all significantly reduced in the SLE group (all p < 0.01).…”

Section: Discussionmentioning

confidence: 99%

“…14,15 The feasibility and reproducibility of STE for LA mechanics have been recently validated. [16][17][18][19] The aims of the present study were: (1) to evaluate LA function and volume by STE-derived strain and strain rate in SLE patients compared to controls, (2) to assess the relationship of LA function and varying grades of LVDD in SLE patients and (3) to investigate effects of some major risk factors on LA function in SLE patients.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of left atrial function by speckle tracking echocardiography in patients with systemic lupus erythematosus

Dai

Qian

et al. 2015

Lupus

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Left atrial (LA) function plays a key role in maintaining optimal cardiac output. Left ventricular diastolic dysfunction (LVDD) has been reported in systemic lupus erythematosus (SLE), but whether LA functional abnormalities also occur in patients with SLE is unknown. Toward this aim we evaluated left atrial function and volume by strain and strain rate derived from speckle tracking echocardiography (STE) and their associations with LVDD. Sixty SLE patients were compared with age- and gender-matched normal controls. The LA strain (S) and strain rate (SR) during systole, early diastole and late diastole (SRs, SRe and SRa, respectively) were measured by STE. The LA volume index (LAVI), traditional parameters of LA and left ventricular diastolic function also were analysed. Global strain and positive SRe were significantly reduced in the SLE group compared with the control group (26.2% ± 9.5% vs 32.5% ± 9.8% and -2.4 ± 1.0 s(-1) vs -3.1 ± 1.2 s(-1), both p < 0.05). The SRs in the SLE and control groups were not significantly different (2.1 ± 0.7 s(-1) vs 2.4 ± 0.8 s(-1), p = 0.2). The positive SRa was increased in the SLE group compared with the control group (-2.1 ± 0.8 s(-1) vs -1.6 ± 0.5 s(-1), p < 0.05) and the LAVI was larger in the SLE group than in the control group (32.4 ± 8.0 vs 25.8 ± 7.1 ml/m(2), p < 0.001). Patients with SLE exhibiting varying grades of LVDD displayed significant differences in LA parameters, including LAVI, SRs, SRe and SRa (all p < 0.05). Multivariate linear analysis additionally revealed that SLICC/ACR damage index (SDI) was independently and inversely associated with global strain, SRs and positive SRe. LA functions were changed in SLE patients, demonstrating impairment in conduit function, decrease in storage function and increase in pump function. Meanwhile, the magnitude of this impairment was predictively associated with the severity of LVDD. The results from this study demonstrate that STE is capable of detecting various aspects of LA functional impairment during SLE progression, and should be further explored as a diagnostic tool for improving the outcomes of SLE patients.

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Left Atrial Functional Remodeling in Lone Atrial Fibrillation: A Two‐Dimensional Speckle Tracking Echocardiographic Study

Cited by 31 publications

References 34 publications

Can We Predict the Outcome of Catheter Ablation for Atrial Fibrillation?

Can We Predict the Outcome of Catheter Ablation for Atrial Fibrillation?

Evaluation of left atrial function in patients with iron-deficiency anemia by two-dimensional speckle tracking echocardiography

Evaluation of left atrial function by speckle tracking echocardiography in patients with systemic lupus erythematosus

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