Left Atrial Systolic Force and Outcome in Asymptomatic Mild to Moderate Aortic Stenosis

Abstract

Higher LASF provides additional prognostic information in patients with asymptomatic mild-to-moderate AS.

Left Atrial Work in Patients with Stable Chronic Heart Failure: Factors Associated and Prognostic Role

“…Similar results were found in other populations such as those of patients with aortic stenosis [19][20][21] or arterial hypertension, 22 where the prognostic power of a parameter of LA systolic performance as LA systolic force resulted as a stronger predictor of adverse CV events than LA size per se. Our results indicate that over 4.1 years the risk of CV death or hospitalization for HF is about 4 times higher in patients with CHF and abnormally high LAKE than CHF and normal LAKE.…”

Left Atrial Volume as Predictor of Valve Replacement and Cardiovascular Events in Patients with Asymptomatic Mild to Moderate Aortic Stenosis

“…14 These findings may suggest that LA volume is an overall marker of the disease severity in AS and a relation to adverse events was expected. 23,24 However, the results of this study demonstrate that even though LA volume is enlarged in asymptomatic patients with mild to moderate disease, a single measure of LA volume is not an independent predictor of AVR or aortic valve related events several years later. This may be explained by the fact that there are several other reasons for increasing LA volume, which may not be strong predictors of valve related adverse events, including AVR.…”

Viewpoint: The ENIGMAS Trial – When Should We Treat Patients with Moderate Aortic Stenosis?

“…Moreover, the included population was not limited to moderate AS patients. A recent substudy from the SEAS trial that was not included in the tables described that increased left atrial systolic force is a marker of increased cardiovascular events at 4.3 years FU . Although cardiologists become more and more familiar with strain techniques with time, few studies clarified the role of strain in AS.…”