Left ventricular and atrial global strain evaluation within subtypes of ventricular remodeling

Abstract

Background: Left ventricular hypertrophy is associated with poor prognosis and adverse events. Left ventricular and left atrial global strain and left atrial reservoir strain (LV-GS; LAGS ; LA-RS) could be used as markers for myocardial function in different forms of ventricular remodeling. The aim of this study was to evaluate LV-GS and LAGS scores in different ventricular remodeling variants and identify risk factors for myo-cardial dysfunction. Methods and Results: This cross-sectional study was divided into four groups of ventricular remodeling: normal geometry, eccentric hypertrophy (EH), concentric hypertrophy (CH) and concentric remodeling (CR). Strain analysis was obtained using standardized protocols. We included 121 subjects, 33 with previous myocardial infarction (MI). We found that EH had the lowest LV-GS and CH the lowest LAGS and LA-RS. Atrial and ventricular dysfunction was present in 40 (33%) and 14 (11.5%) subjects, respectively. Smoking, male sex and previous MI were associated with LV dysfunction and smoking and dyslipidemia with LA dysfunction. EH was closely associated with LV dysfunction and CH with LA dysfunction. Conclusions: We conclude that different types of ventricular geometry had echocardiographic profiles associated with different risk factors for dysfunction assessed by strain. The assessment of ventricular remodeling by global strain could be used as a complementary tool in the echocardiographic evaluation of ventricular and atrial function.