Left Ventricular Assist Device Therapy for Destination Therapy: Is Less Invasive Surgery a Safe Alternative?

Rojas, Sebastián V.; Hanke, Jasmin S.; Avşar, M.; Ahrens, P.; Deutschmann, O.; Tümler, K.; Uribarri, Aitor; Rojas-Hernández, Sara; Sánchez, Pedro L.; González-Santos, José María; Haverich, Axel; Schmitto, Jan D.

doi:10.1016/j.rec.2017.03.023

Cited by 22 publications

(33 citation statements)

References 32 publications

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“…In case of end-stage chronic heart failure, cardiac transplantation is still the therapy of choice, although new treatment strategies have to be developed to overcome the ongoing insufficient donor organ supply. One promising alternative to address the aforementioned issue is the implantation of left ventricular assist devices (LVAD) which is one of the fastest-developing techniques in cardiac surgery, due consistent technological advancements allowing less invasive surgical techniques and miniaturization (10)(11)(12)(13).…”

Section: Original Articlementioning

confidence: 99%

The influence of less invasive ventricular assist device implantation on renal function

et al. 2018

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Section: Original Articlementioning

confidence: 99%

The influence of less invasive ventricular assist device implantation on renal function

et al. 2018

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“…Der operative Zugang erfolgt hierbei über eine links-laterale Thorakotomie sowie eine obere Hemisternotomie [7]. Auch wenn es bis dato keinen eindeutigen wissenschaftlichen Beleg für die Überlegenheit der minimalinvasiven Technik im Vergleich zur konventionellen Operation gibt, wurde in einzelnen Patientenserien eine Reduktion der unmittelbaren chirurgischen Komplikationen wie Blutung oder Rechtsherzversagen bei minimalinvasiv operierten Patienten beschrieben [10]. VAD-Systeme der letzten Generation ermöglichen aktuell ein 2-Jahres-Überleben von über 80 %, was eine deutliche Verbesserung im Vergleich zu den Geräten der ersten Generation von vor 20 Jahren darstellt [13,14].…”

Section: Implantationstechnikunclassified

Assist-Devices bei terminaler Herzinsuffizienz

Rojas¹,

Fox²,

Gummert³

2020

Kardiologie up2date

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“…Clinical overview of the HVAD: a centrifugal continuous-flow ventricular assist device with magnetic and hydrodynamic bearings including lateral implantation strategies successfully developed at the Hannover Medical School and modified by other VAD-programs (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). This article discusses key features of the HVAD, such as its technology, clinical applications and possible future improvements of the pump design.…”

Section: Review Articlementioning

confidence: 99%

Clinical overview of the HVAD: a centrifugal continuous-flow ventricular assist device with magnetic and hydrodynamic bearings including lateral implantation strategies

Chatterjee¹,

Feldmann²,

Dogan³

et al. 2018

J. Thorac. Dis.

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Growing worldwide incidences of end-stage heart failure and declining rates of cardiac transplants have given rise to the need for alternative treatment options, based on mechanical circulatory support (MCS) devices such as left ventricular assist devices (LVADs). Technologically advanced LVADs such as the HVAD (HeartWare, Medtronic) facilitate safe and efficient treatment of heart failure patients with reduced post-operative complications, which is attributed to their considerably miniaturized size. This also facilitates the development and implementation of novel, minimally-invasive surgical techniques. The HVAD is a centrifugal pump, manufactured by HeartWare Inc., (Framingham, MA, USA) and subsequently by Medtronic Inc., (Minnesota, MN, USA), and has been approved for clinical application after receiving the CE Mark approval in 2008 and the FDA approval in 2012. Current research efforts are focused on further miniaturization alongside optimization of electronic and software controllers as well as implementation of the transcutaneous energy transfer (TET) technology. Salient features of the HVAD pump technology, clinical applications and future optimization strategies have been discussed in this article.

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Left Ventricular Assist Device Therapy for Destination Therapy: Is Less Invasive Surgery a Safe Alternative?

Cited by 22 publications

References 32 publications

The influence of less invasive ventricular assist device implantation on renal function

The influence of less invasive ventricular assist device implantation on renal function

Assist-Devices bei terminaler Herzinsuffizienz

Clinical overview of the HVAD: a centrifugal continuous-flow ventricular assist device with magnetic and hydrodynamic bearings including lateral implantation strategies

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