Left ventricular sub-valvar mitral aneurysms

Toit, H. J. Du; Oppell, Ulrich O. von; Hewitson, John; Lawrenson, John; Davies, John Q.

doi:10.1016/s1569-9293(03)00141-5

Cited by 61 publications

(93 citation statements)

References 3 publications

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“…2 Preoperative assessment has previously been done using transthoracic echocardiography, 2-dimensional TEE, and invasive angiography. The addition of 3D TEE allows accurate identification of the SMA neck, improves assessment of the SMA's spatial extent, and provides necessary information regarding mitral valve anatomy 3 and the mechanism of mitral regurgitation.…”

Section: Discussionmentioning

confidence: 99%

Out of Africa

Peters

Khandheria

Patel³

et al. 2013

Circulation

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Section: Discussionmentioning

confidence: 99%

Out of Africa

Peters

Khandheria

Patel³

et al. 2013

Circulation

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“…The majority of these patients are of African ancestry, although similar conditions have been found to a lesser degree in other race groups [ [1], [3] and [4]]. They have also been described as a complication in patients with infective endocarditis, tuberculosis, and syphilis [ [4], [5], [6] and [7]]. Du Toit and colleagues [6] in their series of 12 patients found an association with rheumatic carditis in 2 patients.…”

Section: Commentmentioning

confidence: 95%

“…They have also been described as a complication in patients with infective endocarditis, tuberculosis, and syphilis [ [4], [5], [6] and [7]]. Du Toit and colleagues [6] in their series of 12 patients found an association with rheumatic carditis in 2 patients. The causal effect of all these infections has always been speculative, as it may just reflect the high incidence of the infections in endemic areas, rather than a causal mechanism [6].…”

Section: Commentmentioning

confidence: 99%

Development of a Subaortic Aneurysm Secondary to Disseminated Tuberculosis in a Child

Takawira

Joshi

Plessis

2010

The Annals of Thoracic Surgery

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Subvalvular aneurysms of the left ventricle are very rare and often the cause is uncertain. Very little data in the literature describes subvalvular aneurysms in children and most of the data are derived from case reports. We describe a unique case of a human immunodeficiency virus negative child with a tuberculous subaortic aneurysm observed at different stages of development by serial transthoracic echocardiography. The patient underwent successful cardiac surgery after the initial conservative treatment for tuberculosis (TB).A 3-year-old black boy who was negative for human immunodeficiency virus presented to our institution with a 1-week history of coughing, fever, night sweats, and generalized body swelling. On examination he appeared chronically ill and was underweight for his age. He had generalized lymphadenopathy in the axillary, supraclavicular, cervical, and submandibular regions. He had ascites, hepatomegaly (liver span, 12 cm), and splenomegaly (3 cm below costal margin). The boy was tachypneic with a respiratory rate of 50 breaths/min. He had intercostal and subcostal recession and audible bilateral rhonchi. His heart rate was150 beats/min, with a gallop rhythm present and with muffled heart sounds. There were no murmurs, but he was in congestive cardiac failure. His blood pressure was 80/40 mm Hg.A chest roentgenogram demonstrated cardiomegaly, a widened mediastinum, and paratracheal lymphadenopathy. The C-reactive protein, lactate dehydrogenase levels, and erythrocyte sedimentation rate were elevated. Echocardiography (Fig 1) revealed normal intracardiac anatomy with a large organized and loculated pericardial effusion. A biopsy of a supraclavicular lymph node demonstrated caseating necrosis with sites of granulomatous inflammation. Epitheloid cell granulomas and Langhans giant cells were also seen. The Ziehl Neelsen stain highlighted occasional acid and alcohol fast bacilli, which confirmed the TB. There were no features of lymphoma or malignancy present. Mycobacterium TB was also isolated on cultures of gastric aspirates. A diagnosis of disseminated TB with organized TB pericarditis was made.

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“…The patient was prescribed oral amiodarone and advised surgical resection of submitral aneurysm with mitral valve repair or replacement. 1 …”

Section: Reportmentioning

confidence: 99%

Submitral aneurysm: a rare cause of ventricular tachycardia

Kumar¹,

Balachander²,

Selvaraj³

2012

Heart Asia

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A 42-year-old male presented with sustained ventricular tachycardia of left bundle branch block (LBBB) morphology with left axis deviation (figure 1A) that terminated with amiodarone infusion. He gave a history of episodic palpitations associated with giddiness. Transthoracic and transoesophageal echocardiography showed a wide necked submitral aneurysm measuring 5×5 cm with severe mitral regurgitation (figure 1B,C).Coronary angiogram revealed a dominant right coronary artery with spontaneous dissection of mid and distal segments with splaying of the distal branches overlying the aneurysm ( figure 2A,B). Ventricular tachycardia of right and left bundle branch block morphologies was induced with single ventricular extrastimuli during electrophysiological testing. MRI clearly demonstrated the aneurysm below the mitral valve ( figure 2C,D). The patient was prescribed oral amiodarone and advised surgical resection of submitral aneurysm with mitral valve repair or replacement.1 DISCUSSION Submitral aneurysm is rare outside African blacks and uncommonly presents with ventricular arrhythmias.2 While the aetiology is considered to be congenital, coronary abnormalities have occasionally been described in association with this condition, although the relationship of the coronary abnormality to the aneurysm is unclear in our patient.

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Left ventricular sub-valvar mitral aneurysms

Cited by 61 publications

References 3 publications

Out of Africa

Out of Africa

Development of a Subaortic Aneurysm Secondary to Disseminated Tuberculosis in a Child

Submitral aneurysm: a rare cause of ventricular tachycardia

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